Evidence map›Paper›PMID 34208349›Full record

ArticleMolecules (Basel, Switzerland)2021

Roseabol A, a New Peptaibol from the Fungus

Chang-Kwon Kim, Lauren R H Krumpe, Emily Smith, Curtis J Henrich, Isaac Brownell, Karen L Wendt, Robert H Cichewicz, Barry R O'Keefe, Kirk R Gustafson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Genome-Guided Metabolomic Profiling of Peptaibol-ProducingInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Rare Glutamic Acid Methyl Ester Peptaibols fromInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chang-Kwon KimMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.ORCID 0000-0002-4637-3764
Lauren R H KrumpeMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
Emily SmithMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.ORCID 0000-0001-8869-2336
Curtis J HenrichMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
Isaac BrownellDermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD 20893, USA.ORCID 0000-0002-0090-9914
Karen L WendtNatural Products Discovery Group, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Robert H CichewiczNatural Products Discovery Group, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.ORCID 0000-0003-0744-4117
Barry R O'KeefeMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.ORCID 0000-0003-0772-4856
Kirk R GustafsonMolecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.ORCID 0000-0001-6821-4943
Target (United States) · USUniversity of Oklahoma · USNational Institute of Arthritis and Musculoskeletal and Skin Diseases · US

Funding

Isolation of bioactive proteins from natural product extractsZIABC011472 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI OKEEFE, BARRY · 2012 to 2025
$7.8M
Molecular pathogenesis of Merkel cell carcinomaZIABC011394 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BROWNELL, ISAAC · 2011 to 2021
$6.8M
6 · The paper itself

Abstract

A new 11 amino acid linear peptide named roseabol A (

Indexed as

Amino Acid SequenceAntineoplastic AgentsCarcinoma, Merkel CellCell Line, TumorHumansHypocrealesMagnetic Resonance SpectroscopyMolecular StructurePeptaibolsSkin NeoplasmsAntineoplastic AgentsPeptaibolsClonostachys roseaMerkel cell carcinomapeptaibol

Identifiers

PMID34208349
PMCPMC8231123
OpenAlexW3171632286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.