Evidence map›Paper›PMID 34208273›Full record

ArticleBiomedicines2021

Low Hemoglobin-to-Red Cell Distribution Width Ratio Is Associated with Disease Progression and Poor Prognosis in Upper Tract Urothelial Carcinoma.

Yung-Chun Su, Sheng-Chen Wen, Ching-Chia Li, Hsiao-Chun Su, Hung-Lung Ke, Wei-Ming Li, Hsiang-Ying Lee, Chia-Yang Li, Sheau-Fang Yang, Hung-Pin Tu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yung-Chun SuSchool of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Sheng-Chen WenDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0001-5178-2100
Ching-Chia LiDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Hsiao-Chun SuSchool of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Hung-Lung KeDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Wei-Ming LiDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Hsiang-Ying LeeDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0003-2405-4874
Chia-Yang LiGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0001-5689-9850
Sheau-Fang YangDepartment of Pathology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Hung-Pin TuDepartment of Public Health and Environmental Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0003-1044-2673
Wen-Jeng WuDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Hsin-Chih YehDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0003-4113-629X
Kaohsiung Medical University · TW

Funding

Kaohsiung Medical University KMU-TC108A02Kaohsiung Medical University KMU-TC108B07Kaohsiung Medical University NCTUKMU108-BIO-01-2Kaohsiung Medical University Hospital KMUH-DK-109007Ministry of Science and Technology, Taiwan MOST 109-2314-B-037-095
6 · The paper itself

Abstract

The importance of blood cell markers in patients with malignant tumors has been studied, but there are few studies on the prognostic value of hemoglobin-to-red cell distribution width ratio (HRR) in cancer. This is the first study to investigate the effect of preoperative HRR on patients with upper tract urothelial carcinoma (UTUC). Our retrospective cohort study included 730 UTUC patients who underwent nephroureterectomy from 2000 to 2019. Clinicopathological parameters were compared according to HRR levels, and the relationship between blood cell markers (HRR, white blood cell [WBC] count, platelet count) and prognosis was evaluated using Kaplan-Meier method and Cox regression model. We found that patients with HRR ≤ 1.05 tended to have worse renal function, higher pathological stages, and more high-grade tumors. In univariate analysis, HRR ≤ 1.05, WBC > 8.65 × 10

Indexed as

hemoglobinprognosisprogressionred blood cell distribution widthupper tract urothelial carcinomawhite blood cell count

Identifiers

PMID34208273
PMCPMC8230812
OpenAlexW3166191835

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.