ReviewMolecules (Basel, Switzerland)2021
Trends in the Use of Botanicals in Anti-Aging Cosmetics.
Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and Safety of Topical Application of Plant-Based Products on Skin Aging in Healthy Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of cosmetic dermatology · 2025Pooled it
- A proposed evaluation of new approach methodologies for dermal toxicity assessment of botanicals.Pharmaceutical biology · 2026Review
- GC-MS Profiling, Antioxidant and Enzyme Inhibitory Activities of Basil (Molecules (Basel, Switzerland) · 2026Article
- Liposomes, Niosomes, Ethosomes, and Transethosomes for Curcumin and Chlorogenic Acid Delivery: Formulation Design and Dermal Performance.Antioxidants (Basel, Switzerland) · 2026Review
- Kombucha-Mediated Fermentation Enhances Antioxidant, Anti-Inflammatory, Anti-Ageing and Antimicrobial Properties of Fruit Tree Leaf Agro-Waste Extracts fromInternational journal of molecular sciences · 2026Article
- Unveiling the Bioactive Potential of the Aerial Parts of BalkanPharmaceutics · 2026Article
- Investigating the potential of Ulva rigida extracts as a natural anti-aging agent in cosmetics.Scientific reports · 2026Article
- Phenolic Compounds: From Traditional Uses to Innovative Applications and Everything in Between.Molecular nutrition & food research · 2026Review
- Botanical and Upcycled Bioactives for Advanced Topical Formulations: Mechanistic Pathways, Cutaneous Delivery, and Sustainability-by-Design.Pharmaceutics · 2026Review
- Egyptian National Consensus on Dermocosmetic Ingredient Selection Across Common Dermatology Scenarios: A RAND/UCLA Appropriateness Study.Dermatology and therapy · 2026Article
- Potential side effects of toxic and restricted substances found in cosmetics declared to be of natural origin.Frontiers in public health · 2026Review
- Mechanistic Insights into Flavonoids in Cosmetic Applications: Multifunctional Roles and Formulation Considerations.Clinical, cosmetic and investigational dermatology · 2026Review
- Screening for potential skin benefits of edible botanical extracts on a model associatingBiochemistry and biophysics reports · 2025Article
- Microencapsulated α-Tocopherol and Moringa Extract for Improved Skin Protection: Insights From Human Skin Assessment in Cosmetic Formulations.Journal of cosmetic dermatology · 2025Article
- Review
- Chitosan Nanoparticles Loaded with Polyphenols for Cosmeceutical Applications: A State-of-the-Art Review.Pharmaceutics · 2025Review
- Protective effects of Paeonia suffruticosa callus extract in skin through anti-inflammation and repair UVB-induced damage.International journal of cosmetic science · 2025Article
- Stable and Functional Cosmetic Creams Enriched with Grape Stem Extract: A Sustainable Skincare Strategy.Antioxidants (Basel, Switzerland) · 2025Article
- Article
- Conjugation ofPharmaceutics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Botanical ingredients have been used for thousands of years in skincare for their convenience as well as the diversity and abundance in compounds with biological activity. Among these, polyphenols and especially flavonoids have gained increasing prominence due to their antioxidant and anti-inflammatory properties. In this study, the most used botanical preparations in anti-aging products marketed in 2011 were determined. The analysis was repeated in 2018 for new and reformulated products. The scientific evidence for their application as active ingredients in anti-aging cosmetics and their flavonoid content was also compiled by searching in online scientific databases. Overall, in 2018, there was a noticeable increase in the use of botanical preparations in anti-aging cosmetics. However, the top three botanical species in both years were
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.