Evidence map›Paper›PMID 34208197›Full record

ArticleCancers2021

Multiparametric Integrated

Lale Umutlu, Julian Kirchner, Nils Martin Bruckmann, Janna Morawitz, Gerald Antoch, Marc Ingenwerth, Ann-Kathrin Bittner, Oliver Hoffmann, Johannes Haubold, Johannes Grueneisen and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Hybrid [Bioengineering (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Quantitative imaging in medicine and surgery · 2024
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Breast PET/MRI Hybrid Imaging and Targeted Tracers.Journal of magnetic resonance imaging : JMRI · 2023
    Review
  15. Quantitative imaging in medicine and surgery · 2023
    Article
  16. Review
  17. Article
  18. Review
  19. MultiparametricCancers · 2022
    Article
  20. Clinical Perspectives forMetabolites · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Lale UmutluDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, D-45147 Essen, Germany.
Julian KirchnerDepartment of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty, D-40225 Dusseldorf, Germany.
Nils Martin BruckmannDepartment of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty, D-40225 Dusseldorf, Germany.
Janna MorawitzDepartment of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty, D-40225 Dusseldorf, Germany.
Gerald AntochDepartment of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty, D-40225 Dusseldorf, Germany.
Marc IngenwerthInstitute of Pathology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK) Essen, D-45147 Essen, Germany.
Ann-Kathrin BittnerDepartment Gynecology and Obstetrics, University Hospital Essen, University of Duisburg-Essen, D-45147 Essen, Germany.
Oliver HoffmannDepartment Gynecology and Obstetrics, University Hospital Essen, University of Duisburg-Essen, D-45147 Essen, Germany.
Johannes HauboldDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, D-45147 Essen, Germany.
Johannes GrueneisenDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, D-45147 Essen, Germany.
Harald H QuickErwin L. Hahn Institute for Magnetic Resonance Imaging, University of Duisburg-Essen, D-45141 Essen, Germany.
Christoph RischplerDepartment of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, D-45147 Essen, Germany.
Ken HerrmannDepartment of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, D-45147 Essen, Germany.
Peter GibbsDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Katja Pinker-DomenigDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.ORCID 0000-0002-2722-7331
University of Duisburg-Essen · DEHeinrich Heine University Düsseldorf · DEMemorial Sloan Kettering Cancer Center · USDeutschen Konsortium für Translationale Krebsforschung · DEErwin L. Hahn Institute for Magnetic Resonance Imaging · DE

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Deutsche Forschungsgemeinschaft KI2434/1-2 & BU3075/2-1NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundThis study investigated the performance of simultaneous

methodsOne hundred and twenty-four patients underwent simultaneous

resultsThe highest AUC and accuracy for differentiation between luminal A and B was achieved by all MR sequences (AUC 0.98; accuracy 97.3). The best results in AUC for prediction of hormone receptor status and proliferation rate were found based on all MR and PET data (ER AUC 0.87, PR AUC 0.88, Ki-67 AUC 0.997). PET provided the best determination of grading (AUC 0.71), while all MR and PET analyses yielded the best results for lymphonodular and distant metastatic spread (0.81 and 0.99, respectively).

conclusion

Indexed as

breast cancermultiparametric 18F-FDG PET/MRIradiomicsradiomics-based phenotyping and tumor decoding

Identifiers

PMID34208197
PMCPMC8230865
OpenAlexW3170566791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.