Evidence map›Paper›PMID 34208180›Full record

ArticleMolecules (Basel, Switzerland)2021

Isobornylchalcones as Scaffold for the Synthesis of Diarylpyrazolines with Antioxidant Activity.

Svetlana A Popova, Evgenia V Pavlova, Oksana G Shevchenko, Irina Yu Chukicheva, Aleksandr V Kutchin

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Svetlana A PopovaInstitute of Chemistry, Komi Science Centre, Ural Branch, Russian Academy of Sciences, 48 Pervomayskaya, 167000 Syktyvkar, Russia.
Evgenia V PavlovaInstitute of Chemistry, Komi Science Centre, Ural Branch, Russian Academy of Sciences, 48 Pervomayskaya, 167000 Syktyvkar, Russia.
Oksana G ShevchenkoInstitute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, 28 Kommunisticheskaya, 167982 Syktyvkar, Russia.
Irina Yu ChukichevaInstitute of Chemistry, Komi Science Centre, Ural Branch, Russian Academy of Sciences, 48 Pervomayskaya, 167000 Syktyvkar, Russia.
Aleksandr V KutchinInstitute of Chemistry, Komi Science Centre, Ural Branch, Russian Academy of Sciences, 48 Pervomayskaya, 167000 Syktyvkar, Russia.
Institute of Geology, Komi Science Centre · RURussian Academy of Sciences · RU

Funding

Ministry of Science and Higher Education of the Russian Federation AAAA-A18-118011120004-5Russian Science Foundation 21-73-20091
6 · The paper itself

Abstract

The pyrazoline ring is defined as a "privileged structure" in medicinal chemistry. A variety of pharmacological properties of pyrazolines is associated with the nature and position of various substituents, which is especially evident in diarylpyrazolines. Compounds with a chalcone fragment show a wide range of biological properties as well as high reactivity which is primarily due to the presence of an α, β-unsaturated carbonyl system. At the same time, bicyclic monoterpenoids deserve special attention as a source of a key structural block or as one of the pharmacophore components of biologically active molecules. A series of new diarylpyrazoline derivatives based on isobornylchalcones with different substitutes (MeO, Hal, NO

Indexed as

AnimalsAntioxidantsChalconesChemistry, PharmaceuticalLipid PeroxidationMiceMolecular StructurePyrazolesStructure-Activity RelationshipAntioxidantsChalconesPyrazolesantioxidant activitydiarylpyrazolinesFe2+/ascorbate-initiated lipid peroxidationisobornylchalcones

Identifiers

PMID34208180
PMCPMC8230786
OpenAlexW3171432173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.