Evidence map›Paper›PMID 34208111›Full record

ReviewInternational journal of molecular sciences2021

Anti-PD1/PD-L1 Immunotherapy for Non-Small Cell Lung Cancer with Actionable Oncogenic Driver Mutations.

Edouard Dantoing, Nicolas Piton, Mathieu Salaün, Luc Thiberville, Florian Guisier

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 2 syntheses or guidelines pooled it, 132 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Frontiers in oncology · 2026
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Observational
  16. Molecular and clonal evolution of primary lesionsTranslational lung cancer research · 2025
    Article
  17. Article
  18. [Advances in Targeted Therapy for Advanced Non-small Cell Lung Cancer 
with HER2 Mutation].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025
    Review
  19. Review
  20. Article

37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Edouard DantoingDepartment of Pneumology, CHU Rouen, 76000 Rouen, France.
Nicolas PitonDepartment of Pathology, CHU Rouen, 76000 Rouen, France.ORCID 0000-0001-8779-586X
Mathieu SalaünDepartment of Pneumology, CHU Rouen, 76000 Rouen, France.
Luc ThibervilleDepartment of Pneumology, CHU Rouen, 76000 Rouen, France.
Florian GuisierDepartment of Pneumology, CHU Rouen, 76000 Rouen, France.ORCID 0000-0002-8166-7303
Inserm · FRCentre Hospitalier Universitaire de Rouen · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-PD1/PD-L1 immunotherapy has emerged as a standard of care for stage III-IV non-small cell lung cancer (NSCLC) over the past decade. Patient selection is usually based on PD-L1 expression by tumor cells and/or tumor mutational burden. However, mutations in oncogenic drivers such as

Indexed as

ImmunotherapyAnimalsB7-H1 AntigenCarcinoma, Non-Small-Cell LungHumansLung NeoplasmsMutationOncogenesB7-H1 AntigenALKanti-PD1/PD-L1 immunotherapyBRAFEGFRHER2METnon-small cell lung canceroncogenic driverRETROS1

Identifiers

PMID34208111
PMCPMC8230861
OpenAlexW3170003796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.