ArticleCancers2021
CT Body Composition of Sarcopenia and Sarcopenic Obesity: Predictors of Postoperative Complications and Survival in Patients with Locally Advanced Esophageal Adenocarcinoma.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Sarcopenia and risk of postoperative pneumonia: a systematic review and meta-analysis.The journal of nutrition, health & aging · 2025Pooled it
- The impact of sarcopenia on esophagectomy for cancer: a systematic review and meta-analysis.BMC surgery · 2023Pooled it
- The prognostic value of sarcopenia in oesophageal cancer: A systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2023Pooled it
- Sarcopenic obesity and therapeutic outcomes in gastrointestinal surgical oncology: A meta-analysis.Frontiers in nutrition · 2022Pooled it
- A high ratio of visceral fat area to psoas muscle area predicts poor overall survival for esophageal cancer patients receiving definitive chemoradiotherapy.Surgery today · 2026Article
- Response-adapted perioperative therapy for resectable esophageal cancer in the immunotherapy era: a narrative review.Journal of thoracic disease · 2026Review
- Article
- Impact of Preoperative Sarcopenia on Patient Survival After Esophagectomy for Cancer: A Retrospective Cohort Study.Annals of surgical oncology · 2026Article
- Effectiveness of using simple measures as screening indicators for sarcopenic obesity to predict mortality risk in older male patients: a prospective study.BMC geriatrics · 2026Article
- Tumor-derived MG53 aggravates gastrointestinal cancer cachexia related muscle atrophy by inhibiting the TLR4/PI3K/AKT/FOXO3a signaling pathway.Frontiers in oncology · 2026Article
- Concordance between single-slice abdominal computed tomography-based and bioelectrical impedance-based analysis of body composition in a prospective study.European radiology · 2025Article
- Leveraging Sarcopenia index by automated CT body composition analysis for pan cancer prognostic stratification.NPJ digital medicine · 2025Article
- AI-driven body composition monitoring and its prognostic role in mCRPC undergoing lutetium-177 PSMA radioligand therapy: insights from a retrospective single-center analysis.EJNMMI research · 2025Article
- Development and validation of a CT-measured body composition radiomics model for prognostic assessment in resected pancreatic adenocarcinoma.Scientific reports · 2025Article
- Sarcopenia as a Risk Factor in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt (TIPS) Implantation.Diagnostics (Basel, Switzerland) · 2025Article
- Sarcopenia worsens overall survival following robotic esophagectomy for esophageal cancer.Scientific reports · 2025Article
- Optimization-Incorporated Deep Learning Strategy to Automate L3 Slice Detection and Abdominal Segmentation in Computed Tomography.Bioengineering (Basel, Switzerland) · 2025Article
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- Article
- Effect of Intravenous Contrast on CT Body Composition Measurements in Patients with Intraductal Papillary Mucinous Neoplasm.Diagnostics (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
17 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo assess the impact of body composition imaging biomarkers in computed tomography (CT) on the perioperative morbidity and survival after surgery of patients with esophageal cancer (EC).
methodsEighty-five patients who underwent esophagectomy for locally advanced EC after neoadjuvant therapy between 2014 and 2019 were retrospectively enrolled. Pre- and postoperative CT scans were used to assess the body composition imaging biomarkers (visceral (VAT) and subcutaneous adipose tissue (SAT) areas, psoas muscle area (PMA) and volume (PMV), total abdominal muscle area (TAMA)). Sarcopenia was defined as lumbar skeletal muscle index (LSMI) ≤38.5 cm
resultsPreoperatively, sarcopenia was identified in 58 patients (68.2%), and sarcopenic obesity was present in 7 patients (8.2%). Sarcopenic patients were found to have an elevated risk for the occurrence of major complications (OR: 2.587,
conclusionCT body composition imaging biomarkers can identify high-risk patients with locally advanced esophageal cancer undergoing surgery. Sarcopenic patients have a higher risk of major complications, and patients with sarcopenic obesity are more prone to postoperative pneumonia. Sarcopenia and sarcopenic obesity are both subsequently associated with a prolonged hospitalization. Low preoperative muscle mass and its decrease during the postoperative follow-up are associated with lower DFS and OS.
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