Evidence map›Paper›PMID 34208040›Full record

ArticleInternational journal of molecular sciences2021

Sex and Age-Related Differences in Neuroinflammation and Apoptosis in

Maria Consiglia Trotta, Sami Gharbia, Hildegard Herman, Bianca Mladin, Andrei Hermenean, Cornel Balta, Coralia Cotoraci, Victor Eduard Peteu, Carlo Gesualdo, Francesco Petrillo and 6 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

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  12. Resolution of Inflammation in Retinal Disorders: Briefly the State.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Regulations of Retinal Inflammation: Focusing on Müller Glia.Frontiers in cell and developmental biology · 2022
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Maria Consiglia TrottaSection of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", via Santa Maria di Costantinopoli 16, 80138 Naples, Italy.ORCID 0000-0001-9813-5955
Sami Gharbia"Aurel Ardelean" Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
Hildegard Herman"Aurel Ardelean" Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
Bianca Mladin"Aurel Ardelean" Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
Andrei HermeneanFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Av., 050474 Bucharest, Romania.
Cornel Balta"Aurel Ardelean" Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
Coralia CotoraciFaculty of Medicine, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
Victor Eduard PeteuVictor Babes National Institute of Pathology, 99-101 Splaiul Independentei Av., 050096 Bucharest, Romania.
Carlo GesualdoEye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania "Luigi Vanvitelli", Via Luigi De Crecchio 6, 80138 Naples, Italy.ORCID 0000-0003-4955-7857
Francesco PetrilloDepartment of Ophthalmology, University of Catania, P.zza Università 2, 95131 Catania, Italy.
Marilena GaldieroSection of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", via Santa Maria di Costantinopoli 16, 80138 Naples, Italy.ORCID 0000-0002-0174-0209
Roberto AlfanoDepartment of Advanced Medical and Surgical Sciences "DAMSS", University of Campania "Luigi Vanvitelli", P.zza L. Miraglia 2, 80138 Naples, Italy.
Mihaela GherghiceanuFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Av., 050474 Bucharest, Romania.
Michele D'AmicoSection of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", via Santa Maria di Costantinopoli 16, 80138 Naples, Italy.ORCID 0000-0002-6899-0595
Settimio RossiEye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania "Luigi Vanvitelli", Via Luigi De Crecchio 6, 80138 Naples, Italy.
Anca Hermenean"Aurel Ardelean" Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
University of Campania "Luigi Vanvitelli" · ITVasile Goldis Western University of Arad · ROCarol Davila University of Medicine and Pharmacy · ROInstitutul National Victor Babes · ROUniversity of Catania · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN - 2017TSHBXZMinisterul Cercetării şi Inovării 7PFE/2018Ministerul Cercetării şi Inovării PN 1N/2019_19.29.01.02
6 · The paper itself

Abstract

(1) Background: The pro-resolving lipid mediator Resolvin D1 (RvD1) has already shown protective effects in animal models of diabetic retinopathy. This study aimed to investigate the retinal levels of RvD1 in aged (24 months) and younger (3 months)

Indexed as

Sex CharacteristicsAgingAnimalsApoptosisBiomarkersCaspase 3Docosahexaenoic AcidsEpendymoglial CellsFemaleInflammationMaleMiceMice, Inbred BALB CMicrogliaNF-kappa BRetina3-nitrotyrosineBiomarkersCaspase 3Docosahexaenoic AcidsNF-kappa Bresolvin D1Tumor Necrosis Factor-alphaTyrosineagingapoptosisneuroprotectionretina

Identifiers

PMID34208040
PMCPMC8230628
OpenAlexW3170118332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.