ArticleBiomedicines2021
Intra-Operative Video-Based Measurement of Biaxial Strains of the Ascending Thoracic Aorta.
Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Impact of Dynamic Axial Stretching on the Arterial Pulse Wave Velocity: Physical Foundation and Clinical Implications.Annals of biomedical engineering · 2026Article
- Loss of wall stress homeostasis in ascending thoracic aortic aneurysm: histomorphometric insights into patient variants.The Journal of physiology · 2025Article
- Significance of Dynamic Axial Stretching on Estimating Biomechanical Behavior and Properties of the Human Ascending Aorta.Annals of biomedical engineering · 2024Article
- Article
- Biomechanical Characterisation of Thoracic Ascending Aorta with Preserved Pre-Stresses.Bioengineering (Basel, Switzerland) · 2023Article
- Aortic Aneurysm: Finding the Right Target.Biomedicines · 2023Article
- Existing and Emerging Approaches to Risk Assessment in Patients with Ascending Thoracic Aortic Dilatation.Journal of imaging · 2022Review
Corrections and comments
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Authors and funding
11 authors.
Funding
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Abstract
Local biaxial deformation measurements are essential for the in-depth investigation of tissue properties and remodeling of the ascending thoracic aorta, particularly in aneurysm formation. Current clinical imaging modalities pose limitations around the resolution and tracking of anatomical markers. We evaluated a new intra-operative video-based method to assess local biaxial strains of the ascending thoracic aorta. In 30 patients undergoing open-chest surgery, we obtained repeated biaxial strain measurements, at low- and high-pressure conditions. Precision was very acceptable, with coefficients of variation for biaxial strains remaining below 20%. With our four-marker arrangement, we were able to detect significant local differences in the longitudinal strain as well as in circumferential strain. Overall, the magnitude of strains we obtained (range: 0.02-0.05) was in line with previous reports using other modalities. The proposed method enables the assessment of local aortic biaxial strains and may enable new, clinically informed mechanistic studies using biomechanical modeling as well as mechanobiological profiling.
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