Evidence map›Paper›PMID 34207918›Full record

ArticleJournal of clinical medicine2021

Neutrophil-to-Lymphocyte Ratio and Early Variation of NLR to Predict In-Hospital Mortality and Severity in ED Patients with SARS-CoV-2 Infection.

Laure Abensur Vuillaume, Pierrick Le Borgne, Karine Alamé, François Lefebvre, Lise Bérard, Nicolas Delmas, Lauriane Cipolat, Stéphane Gennai, Pascal Bilbault, Charles-Eric Lavoignet and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Laure Abensur VuillaumeEmergency Department, Regional Hospital of Metz-Thionville, 57000 Metz, France.ORCID 0000-0003-2527-8458
Pierrick Le BorgneEmergency Department, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France.ORCID 0000-0001-9141-6439
Karine AlaméEmergency Department, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France.
François LefebvreDepartment of Public Health, University Hospital of Strasbourg, 67000 Strasbourg, France.
Lise BérardEmergency Department, Haguenau Hospital, 67500 Haguenau, France.
Nicolas DelmasEmergency Department, Colmar Hospital, 68000 Colmar, France.
Lauriane CipolatEmergency Department, Regional Hospital of Metz-Thionville, 57000 Metz, France.
Stéphane GennaiEmergency Department, Reims University Hospital, 51000 Reims, France.
Pascal BilbaultEmergency Department, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France.ORCID 0000-0003-0904-4600
Charles-Eric LavoignetEmergency Department, Hôpital Nord Franche Comté, 90400 Trévenans, France.
On Behalf Of The Crems Network Clinical Research In Emergency Medicine And Sepsis
Centre Hospitalier Régional de Metz-Thionville · FRInserm · FRCentre Hospitalier Universitaire de Reims · FRHopitaux Civils de Colmar · FRHôpitaux Universitaires de Strasbourg · FRL'Hôpital Nord Franche-Comté · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Introduction: The neutrophil-to lymphocyte ratio is valued as a predictive marker in several inflammatory diseases. For example, an increasing NLR is a risk factor of mortality in sepsis. It also appears to be helpful in other settings such as cancer. The aim of our work was to study the prognostic value of NLR for disease severity and mortality in patients infected with SARS-CoV-2 upon their admission to the Emergency Department (ED) and its early variation (ΔNLR) in the first 24 h of management (H-24). (2) Methods: Between 1 March and 30 April 2020, we conducted a multicenter and retrospective cohort study of patients with moderate or severe coronavirus disease 19 (COVID-19), who were all hospitalized after presenting to the ED. (3) Results: A total of 1035 patients were included in our study. Factors associated with infection severity were C-reactive protein level (OR: 1.007, CI 95%: [1.005-1.010],

Indexed as

COVID-19mortalityNLRseverity

Identifiers

PMID34207918
PMCPMC8229672
OpenAlexW3168928157

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.