ReviewInternational journal of molecular sciences2021
Cytokines-Biogenesis and Their Role in Human Breast Milk and Determination.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 41 citations in OpenAlex.
- Microchimerism: The Hidden Cellular Dialogue Between Mother and Fetal That Shapes Lifelong Immunity.Expert reviews in molecular medicine · 2026Review
- A One Health Decalogue for Breastfeeding: Microbiota-Targeted Strategies for Infant Gastrointestinal and Neurodevelopmental Health.Nutrients · 2026Review
- Article
- Quantification and comparison of anti-AAV9 and anti-AAVrh74 antibodies in plasma and human milk: Implications for AAV-based gene therapy candidacy.Journal of neuromuscular diseases · 2025Article
- Adipocytokine profiles in maternal obesity: The impact of lipoinflammation on serum, breastmilk, and infant metabolic development.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2025Review
- Does Breastfeeding Small for Gestational Age Neonates Promote a Healthier Growth Pattern? A Narrative Review.Children (Basel, Switzerland) · 2025Review
- Associations between Parity, History of Breastfeeding, and T-cell Profile of Ovarian Tumors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Impact of Maternal Exposure to SARS-CoV-2 on Immunological Components of Breast Milk.International journal of molecular sciences · 2025Review
- Challenges and Opportunities in Quantifying Bioactive Compounds in Human Breastmilk.Biomolecules · 2025Review
- The Impact of Maternal Chronic Inflammatory Conditions on Breast Milk Composition: Possible Influence on Offspring Metabolic Programming.Nutrients · 2025Review
- Idiopathic Granulomatous Mastitis: Immune-Pathogen Imbalance in a Treatment-Resistant Benign Inflammatory Disease.International journal of women's health · 2025Review
- Bioactive Components of Human Milk and Their Impact on Child's Health and Development, Literature Review.Nutrients · 2024Review
- Which is the optimal choice for neonates' formula or breast milk?Natural products and bioprospecting · 2024Article
- Mammary epithelium permeability during established lactation: associations with cytokine levels in human milk.Frontiers in nutrition · 2024Article
- Understanding the Immunological Quality of Breast Milk in Maternal Overweight and Obesity.Nutrients · 2023Review
- The cellular and immunological dynamics of early and transitional human milk.Communications biology · 2023Article
- Maternal and Neonatal Factors Modulating Breast Milk Cytokines in the First Month of Lactation.Antioxidants (Basel, Switzerland) · 2023Article
- Shaping infant development from the inside out: Bioactive factors in human milk.Seminars in perinatology · 2023Review
- Health concerns about possible long-term effects of legally marketed milk and dairy from animals with intramammary infections.Frontiers in public health · 2023Article
- Case report: Applicability of breastfeeding the child of a patient with kidney failure with replacement therapy.Frontiers in medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Cytokines play a huge role in many biological processes. Their production, release and interactions are subject to a very complex mechanism. Cytokines are produced by all types of cells, they function very differently and they are characterized by synergism in action, antagonism, and aggregation activity, opposing action of one cytokine, overlapping activity, induction of another cytokine, inhibition of cytokine synthesis at the mRNA level as well as autoregulation-stimulation or inhibition of own production. The predominance of pro-inflammatory cytokines leads to a systemic inflammatory response, and anti-inflammatory-to an anti-inflammatory response. They regulate the organism's immune response and protect it against sudden disturbances in homeostasis. The synthesis and activity of cytokines are influenced by the central nervous system through the endocrine system (pituitary gland, adrenal glands).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.