ArticleJournal of clinical medicine2021
Anemia Is a Risk Factor for the Development of Ischemic Stroke and Post-Stroke Mortality.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 58 citations in OpenAlex.
- Mediators of the Association Between Stroke and Blood Cells: A Two-Step Multivariable Mendelian Randomization Study.CNS neuroscience & therapeutics · 2026Article
- Anaemia and long-term outcomes after surgical treatment of uterine fibroids: evidence from real-world data.Journal of thrombosis and thrombolysis · 2026Article
- Machine learning-based prediction model for long-term mortality after ischemic stroke.Scientific reports · 2026Article
- Late bleeding complications after mastectomy and the role of seroma aspiration: a retrospective 12-year cohort study.World journal of surgical oncology · 2026Article
- Effects of anemia on short-term prognosis and imaging features of patients with acute ischemic stroke: preliminary findings.BMC neurology · 2026Article
- Prognostic factors in Sézary syndrome - a retrospective propensity score-matched study on 1277 patients.Frontiers in immunology · 2026Article
- Estimating the burden of anaemia in women of reproductive age attributable to wildfire-sourced fine particulate matter: a multicentre cross-sectional study in low- and middle-income countries.BMJ global health · 2025Article
- Admission anemia and 90-day outcomes after supratentorial intracerebral hemorrhage: a township-level cohort study.European journal of medical research · 2025Article
- Influential factors and predictive model of anemia in hospitalized elderly patients.Scientific reports · 2025Article
- Salicylaldehyde Benzoylhydrazone Protects Against Ferroptosis in Models of Neurotoxicity and Behavioural Dysfunction, In Vitro and In Vivo.Journal of molecular neuroscience : MN · 2025Article
- Anemia and cerebrovascular disease: pathophysiological insights and clinical implications.Annals of medicine and surgery (2012) · 2025Review
- Anemia and outcome of patients with ischemic stroke in a referral hospital in Cameroon.eNeurologicalSci · 2025Article
- Acute Ischemic Stroke Secondary to Severe Anemia From Upper Gastrointestinal Bleeding: A Case Report.Cureus · 2025Article
- Living with a transplanted liver is associated with cytopenias: a nationwide cohort study.Frontiers in gastroenterology (Lausanne, Switzerland) · 2025Article
- Influence of chronic alcohol consumption on cerebral ischemia/reperfusion injury in female mice.Frontiers in cellular neuroscience · 2025Article
- Investigating the contribution of laboratory parameters on plasma neurofilament light chain levels in multiple sclerosis.Frontiers in neurology · 2025Article
- Six-month survival and predictors of mortality after ischemic stroke: A prospective cohort study in Iran.ARYA atherosclerosis · 2025Article
- The impact of perioperative anemia on postoperative delirium after hip fracture surgeries in older adults: a multicenter retrospective cohort study.Frontiers in nutrition · 2025Article
- Peripheral risk factors and their role in biomarker-based screening for dementia in the community.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Impact of Hemoglobin Levels on Composite Cardiac Arrest or Stroke Outcome in Patients With Respiratory Failure Due to COVID-19.Critical care explorations · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundanemia is known to be a risk factor for developing ischemic stroke in long-term follow-up studies, and it is also known to increase the risk of death in ischemic stroke patients. We aimed to determine the association of anemia with the risk of ischemic stroke and the risk of death after ischemic stroke.
methodsThe study included patients from National Health Insurance Service cohort, from January 2005 to December 2015. Anemia patients were defined as those with confirmed diagnostic codes and related medications in the sample cohort, and patients under the age of 18 were excluded. To perform a comparative analysis with the control group, twice as many patients were extracted by propensity score matching. The effects of anemia on the development of ischemic stroke were analyzed.
resultsA total of 58,699 patients were newly diagnosed with anemia during the study period. In anemia group, the rate of ischemic stroke occurring within 1 year was 0.550%, and the rate was 0.272% in the control group. The odds ratio of anemia related to ischemic stroke was 1.602 (95% confidence intervals (CI) 1.363-1.883). During the follow-up period, 175 out of 309 (56.6%) died in anemia group, and 130 out of 314 (41.4%) died in control group. The anemia group showed a higher risk of death than the control group (Hazard ratio 1.509, 95% CI 1.197-1.902).
conclusionAnalysis of the nationwide health insurance data revealed that anemia is one of the risk factors for the development of ischemic stroke, and also an independent prognostic factor affecting post-stroke mortality.
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