ReviewPathogens (Basel, Switzerland)2021
Periodontal Pathogens and Preterm Birth: Current Knowledge and Further Interventions.
Review in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 40 citations in OpenAlex.
- Salivary Prevalence of Four Oral Pathogens in Postpartum Women in Northeast Romania: An Exploratory Cross-Sectional Study.Pathogens (Basel, Switzerland) · 2026Article
- Examining the association of maternal oral health experiences with adverse birth outcomes: findings from Virginia's PRAMS survey.BMC oral health · 2026Article
- Association Between Maternal Periodontitis and Preterm Low Birth Weight in Indian Populations: A Literature Review.International journal of MCH and AIDS · 2026Review
- Review
- The Oral Microbiome and Systemic Health: Bridging the Gap Between Dentistry and Medicine.Cureus · 2025Review
- Dynamic changes in the pregnancy microbiome and their role in preterm birth.Frontiers in cellular and infection microbiology · 2025Review
- Oral Health of 7- to 9-Year-Old Children Born Prematurely-A Case-Control Observational Study with Randomized Case Selection.Dentistry journal · 2024Article
- Pregnant Women's Awareness of Periodontal Disease Effects: A Cross-Sectional Questionnaire Study in Saudi Arabia.Healthcare (Basel, Switzerland) · 2024Article
- The Impact of Periodontal Disease on Preterm Birth and Preeclampsia.Journal of personalized medicine · 2024Review
- Microdiversity of the vaginal microbiome is associated with preterm birth.Nature communications · 2023Article
- Microdiversity of the Vaginal Microbiome is Associated with Preterm Birth.bioRxiv : the preprint server for biology · 2023Article
- Recurrent Pregnancy Loss Etiology, Risk Factors, Diagnosis, and Management. Fresh Look into a Full Box.Journal of clinical medicine · 2023Review
- Oral and periodontal assessment at the first trimester of pregnancy: The PERISCOPE longitudinal study.Acta obstetricia et gynecologica Scandinavica · 2023Observational
- Association between Chronic Gingivitis and Cancer: A Retrospective Cohort Study of 19,782 Outpatients from the United Kingdom.Cancers · 2023Article
- Maternal Periodontal Status as a Factor Influencing Obstetrical Outcomes.Medicina (Kaunas, Lithuania) · 2023Article
- Article
- The bidirectional relationship between periodontal disease and pregnancyFrontiers in microbiology · 2023Review
- Female reproductive tract-organ axes.Frontiers in immunology · 2023Review
- Article
- Clinical chorioamnionitis: where do we stand now?Frontiers in medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preterm labor is defined as a birth before 37 weeks of gestation and occurs in 5-20% of pregnancies. Preterm labor, as multifactorial entity associated with a high risk of neonatal morbidity and mortality, is influenced by maternal, fetal and environmental factors. Microbiological studies suggest that infectious pathogens may account for 25-40% of preterm birth. Infections of different sites, like genital, urinary tract infections, and pneumonia, are linked to the preterm labor. The most recent epidemiological studies consistently report that maternal periodontal disease is associated with preterm delivery, as well as the association between the presence of pathogenic oral bacteria in the placenta and adverse pregnancy outcomes. On the other hand, some previously published papers found periodontal bacteria in placentas of term pregnancies. In spite of a huge research done on the topic, both experimental and clinical, there are many controversial opinions about the role of periodontal infections in preterm birth. Thus, this comprehensive review addresses this very important topic and evaluates novel strategies of preventive and therapeutic approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.