Evidence map›Paper›PMID 34207788›Full record

ArticleAntioxidants (Basel, Switzerland)2021

The Antioxidant Activity of Limonene Counteracts Neurotoxicity Triggered byAβ

Ilaria Piccialli, Valentina Tedeschi, Lucia Caputo, Giuseppe Amato, Laura De Martino, Vincenzo De Feo, Agnese Secondo, Anna Pannaccione

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
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  4. Article
  5. Applications of Limonene in Neoplasms and Non-Neoplastic Diseases.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Article
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  11. Review
  12. Article
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  15. Review
  16. Review
  17. Article
  18. Article
  19. The Essential Oil ofInternational journal of molecular sciences · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ilaria PiccialliDepartment of Neuroscience, Division of Pharmacology, Reproductive and Odontostomatological Sciences, School of Medicine, "Federico II" University of Naples, 80131 Naples, Italy.
Valentina TedeschiDepartment of Neuroscience, Division of Pharmacology, Reproductive and Odontostomatological Sciences, School of Medicine, "Federico II" University of Naples, 80131 Naples, Italy.
Lucia CaputoDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, Italy.ORCID 0000-0003-1352-3102
Giuseppe AmatoDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, Italy.
Laura De MartinoDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, Italy.ORCID 0000-0002-9948-0862
Vincenzo De FeoDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, Italy.ORCID 0000-0002-1070-3207
Agnese SecondoDepartment of Neuroscience, Division of Pharmacology, Reproductive and Odontostomatological Sciences, School of Medicine, "Federico II" University of Naples, 80131 Naples, Italy.
Anna PannaccioneDepartment of Neuroscience, Division of Pharmacology, Reproductive and Odontostomatological Sciences, School of Medicine, "Federico II" University of Naples, 80131 Naples, Italy.
Federico II University Hospital · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many natural-derived compounds, including the essential oils from plants, are investigated to find new potential protective agents in several neurodegenerative disorders such as Alzheimer's disease (AD). In the present study, we tested the neuroprotective effect of limonene, one of the main components of the genus

Indexed as

acetylcholinesteraseAlzheimer’s diseaseAmyloid-β oligomersantioxidant activitylimoneneneuroprotectionpotassium channelsROS

Identifiers

PMID34207788
PMCPMC8227170
OpenAlexW3166427514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.