Evidence map›Paper›PMID 34207756›Full record

ReviewMolecules (Basel, Switzerland)2021

A Multidisciplinary Approach to Coronavirus Disease (COVID-19).

Aliye Gediz Erturk, Arzu Sahin, Ebru Bati Ay, Emel Pelit, Emine Bagdatli, Irem Kulu, Melek Gul, Seda Mesci, Serpil Eryilmaz, Sirin Oba Ilter and 1 more

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aliye Gediz ErturkDepartment of Chemistry, Faculty of Arts and Sciences, Ordu University, Altınordu, Ordu 52200, Turkey.
Arzu SahinDepartment of Basic Medical Sciences-Physiology, Faculty of Medicine, Uşak University, 1-EylulUşak 64000, Turkey.
Ebru Bati AyDepartment of Plant and Animal Production, Suluova Vocational School, Amasya University, Suluova, Amasya 05100, Turkey.
Emel PelitDepartment of Chemistry, Faculty of Arts and Sciences, Kırklareli University, Kırklareli 39000, Turkey.
Emine BagdatliDepartment of Chemistry, Faculty of Arts and Sciences, Ordu University, Altınordu, Ordu 52200, Turkey.
Irem KuluDepartment of Chemistry, Faculty of Basic Sciences, Gebze Technical University, Kocaeli 41400, Turkey.
Melek GulDepartment of Chemistry, Faculty of Arts and Sciences, Amasya University, Ipekkoy, Amasya 05100, Turkey.
Seda MesciScientific Technical Application and Research Center, Hitit University, Çorum 19030, Turkey.
Serpil EryilmazDepartment of Physics, Faculty of Arts and Sciences, Amasya University, Ipekkoy, Amasya 05100, Turkey.ORCID 0000-0002-0935-4644
Sirin Oba IlterFood Processing Department, Suluova Vocational School, Amasya University, Suluova, Amasya 05100, Turkey.
Tuba YildirimDepartment of Biology, Faculty of Arts and Sciences, Amasya University, Ipekkoy, Amasya 05100, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since December 2019, humanity has faced an important global threat. Many studies have been published on the origin, structure, and mechanism of action of the SARS-CoV-2 virus and the treatment of its disease. The priority of scientists all over the world has been to direct their time to research this subject. In this review, we highlight chemical studies and therapeutic approaches to overcome COVID-19 with seven different sections. These sections are the structure and mechanism of action of SARS-CoV-2, immunotherapy and vaccine, computer-aided drug design, repurposing therapeutics for COVID-19, synthesis of new molecular structures against COVID-19, food safety/security and functional food components, and potential natural products against COVID-19. In this work, we aimed to screen all the newly synthesized compounds, repurposing chemicals covering antiviral, anti-inflammatory, antibacterial, antiparasitic, anticancer, antipsychotic, and antihistamine compounds against COVID-19. We also highlight computer-aided approaches to develop an anti-COVID-19 molecule. We explain that some phytochemicals and dietary supplements have been identified as antiviral bioproducts, which have almost been successfully tested against COVID-19. In addition, we present immunotherapy types, targets, immunotherapy and inflammation/mutations of the virus, immune response, and vaccine issues.

Indexed as

Antiviral AgentsBiological ProductsCOVID-19COVID-19 VaccinesCytokine Release SyndromeDrug DesignDrug RepositioningHumansImmunotherapySARS-CoV-2Antiviral AgentsBiological ProductsCOVID-19 VaccinesCOVID-19cytokine stormdietary supplementsimmunotherapyin-silico researchnatural productsrepurposing drugsSARS-CoV-2small drugsvaccine development

Identifiers

PMID34207756
PMCPMC8228528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.