ArticleMaterials (Basel, Switzerland)2021
Drug Carriers Based on Graphene Oxide and Hydrogel: Opportunities and Challenges in Infection Control Tested by Amoxicillin Release.
Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 21 citations in OpenAlex.
- Controlled drug release and electroconductive performance of 3D printed scaffolds for neural tissue regeneration.Journal of materials science. Materials in medicine · 2026Article
- Patient with Inflammatory Bowel Disease in a Dental Office-Which Antibiotic to Choose?-Narrative Review.Journal of clinical medicine · 2025Review
- Nanotherapies based on bacterial metabolism: Mechanisms, design and application.Materials today. Bio · 2025Review
- Graphene-based nanomaterials: mechanisms and potentials in the fight against multidrug resistant bacterial infections: a review.RSC advances · 2025Review
- Nanomaterials: innovative approaches for addressing key objectives in periodontitis treatment.RSC advances · 2024Review
- Applications of graphene oxide and reduced graphene oxide in advanced dental materials and therapies.Journal of Taibah University Medical Sciences · 2024Review
- Graphene as a promising material in orthodontics: A review.Journal of orthodontic science · 2024Review
- Bioactive Endodontic Hydrogels: From Parameters to Personalized Medicine.International journal of molecular sciences · 2023Review
- Can Graphene Pave the Way to Successful Periodontal and Dental Prosthetic Treatments? A Narrative Review.Biomedicines · 2023Review
- Nanomaterials-Based Wound Dressing for Advanced Management of Infected Wound.Antibiotics (Basel, Switzerland) · 2023Review
- The antimicrobial efficacy of graphene oxide, double antibiotic paste, and their combination against Enterococcus faecalis in the root canal treatment.BMC oral health · 2023Article
- Implications of graphene-based materials in dentistry: present and future.Frontiers in chemistry · 2023Review
- Penicillin and Oxacillin Loaded on PEGylated-Graphene Oxide to Enhance the Activity of the Antibiotics against Methicillin-ResistantPharmaceutics · 2022Article
- Peptide-Based Hydrogels: New Materials for Biosensing and Biomedical Applications.Materials (Basel, Switzerland) · 2022Review
- Characteristics of Graphene Oxide for Gene Transfection and Controlled Release in Breast Cancer Cells.International journal of molecular sciences · 2022Review
- Rheological Properties of Different Graphene Nanomaterials in Biological Media.Materials (Basel, Switzerland) · 2022Article
- Graphene-Based Nanomaterials for Dental Applications: Principles, Current Advances, and Future Outlook.Frontiers in bioengineering and biotechnology · 2022Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Graphene oxide (GO) was proposed as an efficient carrier of antibiotics. The model drug, amoxicillin (AMOX), was attached to GO using a peptide linker (Leu-Leu-Gly). GO-AMOX was dispersed in a hydrogel to which the enzyme responsible for releasing AMOX from GO was also added. The drug molecules were released by enzymatic hydrolysis of the peptide bond in the linker. As the selected enzyme, bromelain, a plant enzyme, was used. The antibacterial nature of the carrier was determined by its ability to inhibit the growth of the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.