Evidence map›Paper›PMID 34207701›Full record

Trial reportInternational journal of environmental research and public health2021

Multi-Component Intervention Program on Habitual Physical Activity Parameters and Cognitive Function in Patients with Mild Cognitive Impairment: A Randomized Controlled Trial.

Min-Ki Jeong, Kyung-Won Park, Je-Kwang Ryu, Gwon-Min Kim, Hyun-Hun Jung, Hyuntae Park

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 7 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 7 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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  18. Alteration of Blood Immune Biomarkers in MCI Patients with DifferentInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Min-Ki JeongCollege of Arts and Sports, Dong-A University, Busan 49315, Korea.ORCID 0000-0003-0640-3866
Kyung-Won ParkBusan Metropolitan Dementia Center, Busan 49201, Korea.ORCID 0000-0002-6788-5267
Je-Kwang RyuDepartment of Health Sciences, Graduate School, Dong-A University, Busan 49315, Korea.
Gwon-Min KimHealth Convergence Medicine Laboratory, Biomedical Research Institute, Pusan National University Hospital, Busan 49241, Korea.ORCID 0000-0001-7901-3506
Hyun-Hun JungCollege of Arts and Sports, Dong-A University, Busan 49315, Korea.ORCID 0000-0001-7211-083X
Hyuntae ParkDepartment of Health Sciences, Graduate School, Dong-A University, Busan 49315, Korea.ORCID 0000-0002-1976-0005
Dong-A University · KRNational Center for Geriatrics and Gerontology · JPPusan National University Hospital · KRThe Busan Metropolitan Simin Municipal Library · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related dementia refers to a state in which someone experiences multiple cognitive function impairment due to degenerative brain disease, and which causes difficulties in their daily life or social life. Dementia is the most common and serious obstacle in later life. Early intervention in the case of patients who are in the mild cognitive impairment (MCI) stage among the high-risk group can maintain and improve their cognitive function. The purpose of the current trial is aimed at investigating the association between a multi-component (exercise with cognitive) intervention program and habitual physical activity parameters on cognitive functions in MCI patients. Neuropsychological cognitive and depression assessments were performed by neuropsychologists according to normalized methods, including the Korean mini-mental State examination (K-MMSE) and modified Alzheimer's disease assessment scale-cognitive subscale (ADAS-Cog) and cognitive assessment tool (attention, processing speed), and the Korean version of the geriatric depression scale (SGDS-K), both at baseline and at a 12 weeks follow-up. The 12-week multi-component intervention improved cognitive function and habitual physical activity parameters in patients with MCI relative to controls. A multi-component intervention program for patients with MCI is considered to be an effective method of dementia prevention by improving global (ADAS-Cog) and frontal (trail-making test, digit symbol substitution test) cognition and habitual physical activity parameters such as moderate to vigorous physical activity and step count. In addition, it is important to encourage habitual physical activities to ensure that exercise intervention strategies are carried out at the duration and intensity required for improving physical and cognitive wellbeing and obtaining health benefits.

Indexed as

Cognitive DysfunctionAgedBehavior TherapyCognitionExerciseHumansNeuropsychological Testscognitive functiondementiahabitual physical activity parametersmild cognitive impairmentmulti-component intervention

Identifiers

PMID34207701
PMCPMC8296099
OpenAlexW3173046436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.