Evidence map›Paper›PMID 34207694›Full record

ArticleViruses2021

The Molecular Basis for

Michael J Love, David Coombes, Sarah H Manners, Gayan S Abeysekera, Craig Billington, Renwick C J Dobson

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. The SPI-20 and SPI-21 T6SS gene clusters fromFrontiers in microbiology · 2026
    Article
  3. Review
  4. Recent Advances in Endolysin Engineering.Antibiotics (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Endolysins as Effective Agents for DecontaminatingInternational journal of molecular sciences · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. LysGR1, a novel thermostable endolysin fromFrontiers in microbiology · 2023
    Article
  16. Biocontrol Approaches againstFoods (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Michael J LoveBiomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, Christchurch 8041, New Zealand.
David CoombesBiomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, Christchurch 8041, New Zealand.
Sarah H MannersBiomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, Christchurch 8041, New Zealand.
Gayan S AbeysekeraBiomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, Christchurch 8041, New Zealand.
Craig BillingtonInstitute of Environmental Science and Research, Christchurch 8041, New Zealand.ORCID 0000-0003-3433-4220
Renwick C J DobsonBiomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, Christchurch 8041, New Zealand.ORCID 0000-0002-5506-4939
University of Canterbury · NZNew Zealand Institute for Public Health and Forensic Science · NZThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophage-encoded endolysins have been identified as antibacterial candidates. However, the development of endolysins as mainstream antibacterial agents first requires a comprehensive biochemical understanding. This study defines the atomic structure and enzymatic function of

Indexed as

TemperatureBacteriophagesCrystallography, X-RayEndopeptidasesEnzyme StabilityEscherichia coli O157Models, MolecularProtein EngineeringViral ProteinsendolysinEndopeptidasesViral Proteinsbacteriophageendolysinpeptidoglycan hydrolaseT4 lysozyme

Identifiers

PMID34207694
PMCPMC8228626
OpenAlexW3167389605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.