Evidence map›Paper›PMID 34207646›Full record

ArticleBrain sciences2021

Polymorphisms of

Tsai-Wei Liu, Yih-Ru Wu, Yi-Chun Chen, Hon-Chung Fung, Chiung-Mei Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Review
  3. Bilirubin Prevents the THInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Tsai-Wei LiuDepartment of Neurology, Chang-Gung Memorial Hospital, 5 Fuhsing St., Gueishan, Tauoyan 333, Taiwan.ORCID 0000-0003-1378-824X
Yih-Ru WuDepartment of Neurology, Chang-Gung Memorial Hospital, 5 Fuhsing St., Gueishan, Tauoyan 333, Taiwan.
Yi-Chun ChenDepartment of Neurology, Chang-Gung Memorial Hospital, 5 Fuhsing St., Gueishan, Tauoyan 333, Taiwan.
Hon-Chung FungFu Jen Faculty of Theology of St. Robert Bellarmine, Fu Jen University Clinic, Zhongzheng Rd., Xinzhuang Dist., New Taipei City 242, Taiwan.
Chiung-Mei ChenDepartment of Neurology, Chang-Gung Memorial Hospital, 5 Fuhsing St., Gueishan, Tauoyan 333, Taiwan.ORCID 0000-0002-0769-0353
Chang Gung University · TWChang Gung Memorial Hospital · TWFu Jen Catholic University · TW

Funding

Chang Gung Memorial Hospital, Linkou CMRPG3H147 and CMRPG3J127Ministry of Science and Technology, Taiwan MOST 107-2314-B-182A-045-MY2
6 · The paper itself

Abstract

backgroundStudies have suggested that cytokines are crucial mediators in the pathogenesis of Parkinson's disease (PD). The multifunctional cytokine interleukin (IL)-6 and its single nucleotide polymorphisms (SNPs) were found to have an impact on the development of PD. However, different studies in associations of

methodsThis study examined the frequencies of polymorphisms within the critical promoter areas of the proinflammatory cytokine genes:

resultsIn total, 1120 subjects, including 509 PD patients (female/male: 259/250) and 511 control subjects (female/male: 252/259), were recruited. We found no statistically significant differences in

conclusionsThe results did not demonstrate any association of

Indexed as

disease associationgenetic polymorphismIL-6IL-8inflammationParkinson’s disease

Identifiers

PMID34207646
PMCPMC8229237
OpenAlexW3170190507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.