Evidence map›Paper›PMID 34207575›Full record

ArticlePathogens (Basel, Switzerland)2021

Francesca Necchi, Giuseppe Stefanetti, Renzo Alfini, Elena Palmieri, Martina Carducci, Roberta Di Benedetto, Fabiola Schiavo, Maria Grazia Aruta, Fabiola Giusti, Ilaria Ferlenghi and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Francesca NecchiGSK Vaccines Institute for Global Health, 53100 Siena, Italy.
Giuseppe StefanettiGSK Vaccines Institute for Global Health, 53100 Siena, Italy.ORCID 0000-0002-2796-4817
Renzo AlfiniGSK Vaccines Institute for Global Health, 53100 Siena, Italy.
Elena PalmieriGSK Vaccines Institute for Global Health, 53100 Siena, Italy.ORCID 0000-0002-1248-5389
Martina CarducciGSK Vaccines Institute for Global Health, 53100 Siena, Italy.ORCID 0000-0001-6633-567X
Roberta Di BenedettoGSK Vaccines Institute for Global Health, 53100 Siena, Italy.
Fabiola SchiavoGSK Vaccines Institute for Global Health, 53100 Siena, Italy.ORCID 0000-0002-2574-460X
Maria Grazia ArutaGSK Vaccines Institute for Global Health, 53100 Siena, Italy.
Fabiola GiustiGSK, 53100 Siena, Italy.
Ilaria FerlenghiGSK, 53100 Siena, Italy.
Yun Shan GohGSK Vaccines Institute for Global Health, 53100 Siena, Italy.
Simona RondiniGSK Vaccines Institute for Global Health, 53100 Siena, Italy.
Francesca MicoliGSK Vaccines Institute for Global Health, 53100 Siena, Italy.
Toscana Life Sciences · ITAgency for Science, Technology and Research · SGHarvard University · USUniversity of Milan · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GMMA, outer membrane vesicles resulting from hyperblebbing mutated bacterial strains, are a versatile vaccine platform for displaying both homologous and heterologous antigens. Periplasmic expression is a popular technique for protein expression in the lumen of the blebs. However, the ability of internalized antigens to induce antibody responses has not been extensively investigated. Herein, the

Indexed as

fHbpGMMANeisseria meningitidisSalmonella

Identifiers

PMID34207575
PMCPMC8229706
OpenAlexW3166423592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.