Evidence map›Paper›PMID 34207560›Full record

ArticleInternational journal of environmental research and public health2021

Using Machine Learning Algorithms to Develop a Clinical Decision-Making Tool for COVID-19 Inpatients.

Abhinav Vepa, Amer Saleem, Kambiz Rakhshan, Alireza Daneshkhah, Tabassom Sedighi, Shamarina Shohaimi, Amr Omar, Nader Salari, Omid Chatrabgoun, Diana Dharmaraj and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
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  5. Article
  6. COVID-Transformer: Interpretable COVID-19 Detection Using Vision Transformer for Healthcare.International journal of environmental research and public health · 2021
    Article
  7. Article
  8. Economic Evaluation of Mental Health Effects of Flooding Using Bayesian Networks.International journal of environmental research and public health · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 3 countries.

Abhinav VepaMilton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.ORCID 0000-0001-5858-1109
Amer SaleemMilton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.ORCID 0000-0002-0550-3534
Kambiz RakhshanLeeds Sustainability Institute, Leeds Beckett University, Leeds LS1 3HE, UK.ORCID 0000-0001-9582-1693
Alireza DaneshkhahResearch Centre for Computational Science and Mathematical Modelling, Coventry University, Coventry CV1 5FB, UK.
Tabassom SedighiCentre for Environment and Agricultural Informatics, Cranfield University, Bedfordshire MK43 0AL, UK.
Shamarina ShohaimiDepartment of Biology, Faculty of Science, University Putra Malaysia, Serdang, Selangor 43400, Malaysia.ORCID 0000-0003-0591-6627
Amr OmarMilton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.
Nader SalariDepartment of Biostatistics, School of Health, Kermanshah University of Medical Sciences, Kermanshah 6715847141, Iran.
Omid ChatrabgounFaculty of Mathematical Sciences & Statistics, Malayer University, Malayer 6571995863, Iran.ORCID 0000-0001-5025-4760
Diana DharmarajMilton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.
Junaid SamiMilton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.
Shital ParekhMilton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.
Mohamed IbrahimMilton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.
Mohammed RazaMilton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.
Poonam KapilaMilton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.
Prithwiraj ChakrabartiMilton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.
Milton Keynes Hospital · GBCoventry University · GBCranfield University · GBKermanshah University of Medical Sciences · IRLeeds Beckett University · GBMalayer University · IRUniversiti Putra Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWithin the UK, COVID-19 has contributed towards over 103,000 deaths. Although multiple risk factors for COVID-19 have been identified, using this data to improve clinical care has proven challenging. The main aim of this study is to develop a reliable, multivariable predictive model for COVID-19 in-patient outcomes, thus enabling risk-stratification and earlier clinical decision-making.

methodsAnonymised data consisting of 44 independent predictor variables from 355 adults diagnosed with COVID-19, at a UK hospital, was manually extracted from electronic patient records for retrospective, case-control analysis. Primary outcomes included inpatient mortality, required ventilatory support, and duration of inpatient treatment. Pulmonary embolism sequala was the only secondary outcome. After balancing data, key variables were feature selected for each outcome using random forests. Predictive models were then learned and constructed using Bayesian networks.

resultsThe proposed probabilistic models were able to predict, using feature selected risk factors, the probability of the mentioned outcomes. Overall, our findings demonstrate reliable, multivariable, quantitative predictive models for four outcomes, which utilise readily available clinical information for COVID-19 adult inpatients. Further research is required to externally validate our models and demonstrate their utility as risk stratification and clinical decision-making tools.

Indexed as

COVID-19InpatientsAdultAlgorithmsBayes TheoremClinical Decision-MakingHumansMachine LearningRetrospective StudiesSARS-CoV-2Bayesian networkCOVID-19random forestrisk stratificationSARS CoVsynthetic minority oversampling technique (SMOTE)

Identifiers

PMID34207560
PMCPMC8296041
OpenAlexW3166303156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.