Evidence map›Paper›PMID 34207517›Full record

ReviewInternational journal of molecular sciences2021

Diabetes Mellitus and Its Implications in Aortic Stenosis Patients.

Laura Mourino-Alvarez, Nerea Corbacho-Alonso, Tamara Sastre-Oliva, Cecilia Corros-Vicente, Jorge Solis, Teresa Tejerina, Luis R Padial, Maria G Barderas

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Impact of cardiovascular comorbidities on echocardiographic parameters in aortic stenosis.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025
    Article
  5. Article
  6. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Laura Mourino-AlvarezDepartment of Vascular Physiopathology, Hospital Nacional de Paraplejicos (HNP), SESCAM, 45071 Toledo, Spain.
Nerea Corbacho-AlonsoDepartment of Vascular Physiopathology, Hospital Nacional de Paraplejicos (HNP), SESCAM, 45071 Toledo, Spain.
Tamara Sastre-OlivaDepartment of Vascular Physiopathology, Hospital Nacional de Paraplejicos (HNP), SESCAM, 45071 Toledo, Spain.
Cecilia Corros-VicenteDepartment of Vascular Physiopathology, Hospital Nacional de Paraplejicos (HNP), SESCAM, 45071 Toledo, Spain.
Jorge SolisDepartment of Cardiology, Hospital Universitario 12 de Octubre and Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), 28041 Madrid, Spain.
Teresa TejerinaDepartment of Pharmacology, School of Medicine, Universidad Complutense, 28040 Madrid, Spain.
Luis R PadialDepartment of Cardiology, Hospital Virgen de la Salud, SESCAM, 45004 Toledo, Spain.
Maria G BarderasDepartment of Vascular Physiopathology, Hospital Nacional de Paraplejicos (HNP), SESCAM, 45071 Toledo, Spain.ORCID 0000-0003-4290-4721
Servicio de Salud de Castilla La Mancha · ESHospital Virgen de la Salud · ESInstituto de Salud Carlos III · ESUniversidad Complutense de Madrid · ES

Funding

Instituto de Salud Carlos III PI18/00995; FI19/00157; Grant PRB3 (IPT17/0019 - ISCIII-SGEFI / ERDF)
6 · The paper itself

Abstract

Aortic stenosis (AS) and diabetes mellitus (DM) are both progressive diseases that if left untreated, result in significant morbidity and mortality. Several studies revealed that the prevalence of DM is substantially higher in patients with AS and, thus, the progression from mild to severe AS is greater in those patients with DM. DM and common comorbidities associated with both diseases, DM and AS, increase patient management complexity and make aortic valve replacement the only effective treatment. For that reason, a better understanding of the pathogenesis underlying both these diseases and the relationships between them is necessary to design more appropriate preventive and therapeutic approaches. In this review, we provided an overview of the main aspects of the relationship between AS and DM, including common comorbidities and risk factors. We also discuss the established treatments/therapies in patients with AS and DM.

Indexed as

Aortic Valve StenosisDiabetes ComplicationsHumansRisk Factorsaortic stenosiscalcificationdiabetes mellitusrisk prediction

Identifiers

PMID34207517
PMCPMC8227301
OpenAlexW3172839444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.