Evidence map›Paper›PMID 34207425›Full record

ArticleMicroorganisms2021

Dental Biofilm and Saliva Microbiome and Its Interplay with Pediatric Allergies.

Nicole B Arweiler, Vivien Rahmel, Bilal Alashkar Alhamwe, Fahd Alhamdan, Michael Zemlin, Sébastien Boutin, Alexander Dalpke, Harald Renz

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Exploring Oral Microbiome in Healthy Infants and Children: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Review
  3. Oral microbiota related to allergy in Norwegian adults.The journal of allergy and clinical immunology. Global · 2025
    Article
  4. Review
  5. Review
  6. Association between Asthma and Periodontitis.Diagnostics (Basel, Switzerland) · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Relationship between Saliva and Sublingual Immunotherapy.Pathogens (Basel, Switzerland) · 2021
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Nicole B ArweilerDepartment of Periodontology and Peri-Implant Diseases, Philipps University Marburg, 35039 Marburg, Germany.ORCID 0000-0003-1453-0697
Vivien RahmelDepartment of Periodontology and Peri-Implant Diseases, Philipps University Marburg, 35039 Marburg, Germany.
Bilal Alashkar AlhamweInstitute of Tumor Immunology, Clinic for Hematology, Oncology and Immunology, Center for Tumor Biology and Immunology, Philipps University Marburg, 35039 Marburg, Germany.ORCID 0000-0001-5449-7989
Fahd AlhamdanInstitute of Laboratory Medicine, Philipps University Marburg, Member of the German Center for Lung Research (DZL), 35039 Marburg, Germany.
Michael ZemlinDepartment for General Pediatrics and Neonatology, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0000-0001-9528-7419
Sébastien BoutinDepartment of Infectious Diseases, Medical Microbiology and Hygiene, University Heidelberg, 69120 Heidelberg, Germany.
Alexander DalpkeInstitute of Medical Microbiology and Virology, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, 01307 Dresden, Germany.ORCID 0000-0003-1648-6618
Harald RenzInstitute of Laboratory Medicine, Philipps University Marburg, Member of the German Center for Lung Research (DZL), 35039 Marburg, Germany.ORCID 0000-0003-0602-7215
Philipps University of Marburg · DEGerman Center for Lung Research · DEHeidelberg University · DESaarland University · DEUniversity Hospital Carl Gustav Carus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Little is known about the interplay and contribution of oral microorganisms to allergic diseases, especially in children. The aim of the clinical study was to associate saliva and dental biofilm microbiome with allergic disease, in particular with allergic asthma. In a single-center study, allergic/asthmatic children (

Indexed as

16s-rRNA gene next-generation sequencingbiofilm metabolismdental biofilmoral microbiomesaliva

Identifiers

PMID34207425
PMCPMC8235788
OpenAlexW3175934236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.