ArticlePharmaceuticals (Basel, Switzerland)2021
Protective Effect of Piplartine against LPS-Induced Sepsis through Attenuating the MAPKs/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation.
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Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Natural Products as NLRP3 Inflammasome Inhibitors: A Review.Molecules (Basel, Switzerland) · 2026Review
- Rosamultin Alleviates LPS-Induced Acute Kidney Injury by Promoting Autophagy and Inhibiting the NF-κB Signaling Pathway.Drug design, development and therapy · 2026Article
- Anti-Inflammatory Effect of 21Food science & nutrition · 2025Article
- Cordycepin attenuates NLRP3/Caspase-1/GSDMD-mediated LPS-induced macrophage pyroptosis.Frontiers in pharmacology · 2025Article
- Protective effects of nordalbergin against LPS-induced endotoxemia through inhibiting MAPK/NF-κB signaling pathway, NLRP3 inflammasome activation, and ROS production.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024Article
- Levosimendan and Dobutamin Attenuate LPS-Induced Inflammation in Microglia by Inhibiting the NF-κB Pathway and NLRP3 Inflammasome Activation via Nrf2/HO-1 Signalling.Biomedicines · 2024Article
- Role and mechanism of endoplasmic reticulum stress and NLRP3 inflammasome in acute kidney injury.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Review
- Prognostic value of inflammatory cytokine detection for sepsis patients in ICU: a meta-analysis.American journal of translational research · 2024Review
- Host and Pathogen-Directed Therapies against Microbial Infections Using Exosome- and Antimicrobial Peptide-derived Stem Cells with a Special look at Pulmonary Infections and Sepsis.Stem cell reviews and reports · 2023Review
- Kinetic simulation study of femtosecond laser processing of graphene oxide: first-principles.Journal of molecular modeling · 2023Article
- Inhibition of LPS‑induced NLRP3 inflammasome activation by stem cell‑conditioned culture media in human gingival epithelial cells.Molecular medicine reports · 2023Article
- Effects of piperlonguminine on lung injury in severe acute pancreatitis <em>via</em> the TLR4/NF-κB pathway.European journal of histochemistry : EJH · 2023Article
- Article
- Calcium dobesilate alleviates renal dysfunction and inflammation by targeting nuclear factor kappa B (NF-κB) signaling in sepsis-associated acute kidney injury.Bioengineered · 2022Article
- Correlation Analysis of Blood Glucose Level with Inflammatory Response and Immune Indicators in Patients with Sepsis.Disease markers · 2022Article
- Anti-inflammatory and anti-oxidant properties of Melianodiol on DSS-induced ulcerative colitis in mice.PeerJ · 2022Article
- Genomic analysis quantifies pyroptosis in the immune microenvironment of HBV-related hepatocellular carcinoma.Frontiers in immunology · 2022Article
- Punicalagin Attenuates LPS-Induced Inflammation and ROS Production in Microglia by Inhibiting the MAPK/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation.Journal of inflammation research · 2022Article
- [Antibacterial mechanism of Brevinin-2GHk, an antimicrobial peptide fromNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- Article
Corrections and comments
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Authors and funding
16 authors at 3 institutions in 1 country.
Chi-Han HuangGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0002-3393-1587
Shu-Chi WangDepartment of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0001-9691-7507
I-Chen ChenGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0002-9770-8544
Yi-Ting ChenGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Po-Len LiuDepartment of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0003-2896-1666
Shih-Hua FangInstitute of Athletics, National Taiwan University of Sport, Taichung 40404, Taiwan.
Shu-Pin HuangDepartment of Urology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Hsin-Chih YehDepartment of Urology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0003-4113-629X
Ching-Chih LiuGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Po-Yen LeeGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0002-1825-0003
Tzu-Chieh LinGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Wei-Chung ChengGraduate Institute of Biomedical Science, Research Center for Cancer Biology, China Medical University, Taichung 40403, Taiwan.ORCID 0000-0002-1229-4857
Chia-Cheng SuGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Hsin-En WuGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Yuan-Ru ChenGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Chia-Yang LiGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0001-5689-9850
Kaohsiung Medical University · TWChina Medical University · TWNational Taiwan University of Sport · TW
Funding
China Medical University, Taiwan CMU107-S-24, CMU108-Z-02 and CMU109-MF-61Ministry of Science and Technology, Taiwan MOST 108-2314-B-037 -079-MY3, MOST 109-2622-E-039-004-CC2, MOST 109-2628-E-039-001-MY3, MOST 109-2327-B-039-002 and MOST 109-2320-B-037-007-MY3
Abstract
Piplartine (or Piperlongumine) is a natural alkaloid isolated from
Indexed as
inflammationmacrophageNLRP3 inflammasomepiplartinesepsis
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.