Evidence map›Paper›PMID 34207320›Full record

ArticleMolecules (Basel, Switzerland)2021

The Evaluation of Multiple Linear Regression-Based Limited Sampling Strategies for Mycophenolic Acid in Children with Nephrotic Syndrome.

Joanna Sobiak, Matylda Resztak, Maria Chrzanowska, Jacek Zachwieja, Danuta Ostalska-Nowicka

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Joanna SobiakDepartment of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, 60-781 Poznań, Poland.ORCID 0000-0002-2764-1575
Matylda ResztakDepartment of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, 60-781 Poznań, Poland.
Maria ChrzanowskaDepartment of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, 60-781 Poznań, Poland.
Jacek ZachwiejaDepartment of Pediatric Nephrology and Hypertension, Poznan University of Medical Sciences, 60-572 Poznań, Poland.
Danuta Ostalska-NowickaDepartment of Pediatric Nephrology and Hypertension, Poznan University of Medical Sciences, 60-572 Poznań, Poland.
Poznan University of Medical Sciences · PL

Funding

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu 502-14-03306413-10156
6 · The paper itself

Abstract

We evaluated mycophenolic acid (MPA) limited sampling strategies (LSSs) established using multiple linear regression (MLR) in children with nephrotic syndrome treated with mycophenolate mofetil (MMF). MLR-LSS is an easy-to-determine approach of therapeutic drug monitoring (TDM). We assessed the practicability of different LSSs for the estimation of MPA exposure as well as the optimal time points for MPA TDM. The literature search returned 29 studies dated 1998-2020. We applied 53 LSSs (

Indexed as

AdolescentBlood Specimen CollectionChildChild, PreschoolChromatography, High Pressure LiquidFemaleHumansKidney TransplantationLinear ModelsMaleMultivariate AnalysisMycophenolic AcidNephrotic SyndromeSpecimen HandlingMycophenolic Acidlimited sampling strategymultiple linear regressionmycophenolate mofetilmycophenolic acidpediatric patientstherapeutic drug monitoring

Identifiers

PMID34207320
PMCPMC8235059
OpenAlexW3176643382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.