Evidence map›Paper›PMID 34207237›Full record

ArticleBiomedicines2021

Allergen Exposure in Murine Neonates Promoted the Development of Asthmatic Lungs.

Jeng-Chang Chen, Cheng-Chi Chan, Nai-Chun Ting, Ming-Ling Kuo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jeng-Chang ChenDepartment of Surgery, Chang Gung Children's Hospital, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-7776-4338
Cheng-Chi ChanAbnova Corporation, Taipei 114, Taiwan.ORCID 0000-0002-6866-4503
Nai-Chun TingGraduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Ming-Ling KuoDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Chang Gung University · TW

Funding

Chang Gung Memorial Hospital CMRPG3G1501-3 and CMRPG3J1111-2 (J.-C.C.)Department of Education, Taiwan CMRPD1L0011 and CMRPF1K0261-2 (M.-L.K.)Ministry of Science and Technology, Taiwan 109-2314-B-182-041-MY3 (J.-C.C.); 107-2320-B-182-005-MY3 (M.-L.K.)
6 · The paper itself

Abstract

We previously demonstrated that fetal allergen exposure caused T-helper 2 (Th2) cell sensitization. Although neonates are immunologically more mature than fetuses, asthmatic lungs were reportedly mitigated by neonatal allergen administration, mechanically referring to regulatory T-cells and TGF-

Indexed as

adjuvantasthmachemokinecytokineneonateovalbuminsensitization

Identifiers

PMID34207237
PMCPMC8235458
OpenAlexW3176215327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.