Evidence map›Paper›PMID 34207168›Full record

ArticleMolecules (Basel, Switzerland)2021

Effect of 1-Carbaldehyde-3,4-dimethoxyxanthone on Prostate and HPV-18 Positive Cervical Cancer Cell Lines and on Human THP-1 Macrophages.

Rui Medeiros, Bruno Horta, Joana Freitas-Silva, Jani Silva, Francisca Dias, Emília Sousa, Madalena Pinto, Fátima Cerqueira

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rui MedeirosMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.ORCID 0000-0003-3010-8373
Bruno HortaMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.ORCID 0000-0003-2769-8958
Joana Freitas-SilvaCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal.ORCID 0000-0002-0235-4991
Jani SilvaMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Francisca DiasMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.ORCID 0000-0002-4993-4467
Emília SousaCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal.ORCID 0000-0002-5397-4672
Madalena PintoCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal.ORCID 0000-0002-4676-1409
Fátima CerqueiraMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Universidade do Porto · PTFernando Pessoa University · PTInstituto Português de Oncologia Francisco Gentil · PT

Funding

Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-016790; Project 3599Fundação para a Ciência e a Tecnologia UID/Multi/04546/2019Fundação para a Ciência e a Tecnologia UIDP/04423/2020
6 · The paper itself

Abstract

Xanthone derivatives have shown promising antitumor properties, and 1-carbaldehyde-3,4-dimethoxyxanthone (

Indexed as

AnimalsAntineoplastic AgentsCell LineCell Line, TumorCytokinesFemaleHeLa CellsHuman papillomavirus 18HumansJurkat CellsMacrophagesMaleMiceNitric OxidePC-3 CellsProstateAntineoplastic AgentsCytokinesNitric OxidexanthoneXanthones1-carbaldehyde-3,4-dimethoxyxanthoneantitumorcervical cancercytokinesimmunomodulationmacrophage functionsprostate cancer

Identifiers

PMID34207168
PMCPMC8235309
OpenAlexW3174504876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.