Evidence map›Paper›PMID 34206974›Full record

ArticleBiology2021

Label-Free Single Cell Viability Assay Using Laser Interference Microscopy.

Yulia Beloglazova, Aleksandr Nikitiuk, Anna Voronina, Olga Gagarskikh, Yuriy Bayandin, Oleg Naimark, Victoria Grishko

Open access · goldAbstract read
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yulia BeloglazovaPerm Federal Scientific Centre, Institute of Technical Chemistry UB RAS, Academician Korolev St. 3, 614013 Perm, Russia.ORCID 0000-0003-1141-6266
Aleksandr NikitiukPerm Federal Scientific Centre, Institute of Continuous Media Mechanics UB RAS, Academician Korolev St. 1, 614013 Perm, Russia.
Anna VoroninaPerm Federal Scientific Centre, Institute of Technical Chemistry UB RAS, Academician Korolev St. 3, 614013 Perm, Russia.
Olga GagarskikhPerm Federal Scientific Centre, Institute of Technical Chemistry UB RAS, Academician Korolev St. 3, 614013 Perm, Russia.ORCID 0000-0001-6802-5384
Yuriy BayandinPerm Federal Scientific Centre, Institute of Continuous Media Mechanics UB RAS, Academician Korolev St. 1, 614013 Perm, Russia.
Oleg NaimarkPerm Federal Scientific Centre, Institute of Continuous Media Mechanics UB RAS, Academician Korolev St. 1, 614013 Perm, Russia.
Victoria GrishkoPerm Federal Scientific Centre, Institute of Technical Chemistry UB RAS, Academician Korolev St. 3, 614013 Perm, Russia.ORCID 0000-0003-0765-0244
Institute of Technical Chemistry · RUInstitute of Continuous Media Mechanics · RU

Funding

Ministry of Science and Higher Education of the Russian Federation RFMEFI60718X0202
6 · The paper itself

Abstract

Laser interference microscopy (LIM) is a promising label-free method for single-cell research applicable to cell viability assessment in the studies of mammalian cells. This paper describes the development of a sensitive and reproducible method for assessing cell viability using LIM. The method, based on associated signal processing techniques, has been developed as a result of real-time investigation in phase thickness fluctuations of viable and non-viable MCF-7 cells, reflecting the presence and absence of their metabolic activity. As evinced by the values of the variable

Indexed as

cell viability assayFourier analysislaser interference microscopyMCF-7multifractal analysisnon-invasivewavelet analysis

Identifiers

PMID34206974
PMCPMC8301067
OpenAlexW3174812717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.