Evidence map›Paper›PMID 34206933›Full record

ArticleAnimals : an open access journal from MDPI2021

A DNA Regulatory Element Haplotype at Zinc Finger Genes Is Associated with Host Resilience to Small Ruminant Lentivirus in Two Sheep Populations.

Alisha T Massa, Michelle R Mousel, Codie J Durfee, Maria K Herndon, Kaneesha M Hemmerling, J Bret Taylor, Holly L Neibergs, Stephen N White

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alisha T MassaDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99163, USA.ORCID 0000-0002-5098-7494
Michelle R MouselAnimal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, WA 99163, USA.
Codie J DurfeeAnimal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, WA 99163, USA.
Maria K HerndonDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99163, USA.
Kaneesha M HemmerlingDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99163, USA.
J Bret TaylorRange Sheep Production Efficiency Research, Agricultural Research Service, United States Department of Agriculture, Dubois, ID 83423, USA.
Holly L NeibergsDepartment of Animal Science, Washington State University, Pullman, WA 99163, USA.ORCID 0000-0001-8121-3072
Stephen N WhiteAnimal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, WA 99163, USA.ORCID 0000-0001-9255-6054
Agricultural Research Service · USWashington State University · US

Funding

USDA, Agricultural Research Service 2090-32000-036-00D
6 · The paper itself

Abstract

Small ruminant lentivirus (SRLV) causes Maedi-Visna or Ovine Progressive Pneumonia in sheep and creates insidious livestock production losses. This retrovirus is closely related to human immunodeficiency virus and currently has no vaccines or cure. Genetic marker assisted selection for sheep disease resiliency presents an attractive management solution. Previously, we identified a region containing a cluster of zinc finger genes that had association with ovine SRLV proviral concentration. Trait-association analysis validated a small insertion/deletion variant near

Indexed as

genetic fine mappost-infection controlsheepsmall ruminant lentivirusvalidation

Identifiers

PMID34206933
PMCPMC8300134
OpenAlexW3175852506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.