Evidence map›Paper›PMID 34206923›Full record

ReviewJournal of clinical medicine2021

The Role of Physiotherapy in the New Treatment Landscape for Haemophilia.

Sébastien Lobet, Merel Timmer, Christoph Königs, David Stephensen, Paul McLaughlin, Gaetan Duport, Cédric Hermans, Maria Elisa Mancuso

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Managing Haemophilic Arthropathy in People With Haemophilia in Japan: An Informal Consensus.Haemophilia : the official journal of the World Federation of Hemophilia · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The evolution of physiotherapy in the multidisciplinary management of persons with haemophilia (PWH): A scoping review.Haemophilia : the official journal of the World Federation of Hemophilia · 2023
    Article
  9. Promoting physical activity for people with haemophilia in the age of new treatments.Haemophilia : the official journal of the World Federation of Hemophilia · 2022
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 6 countries.

Sébastien LobetHemostasis and Thrombosis Unit, Division of Hematology, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium.ORCID 0000-0002-3829-6850
Merel TimmerVan Creveldkliniek, University Medical Center Utrecht, Utrecht University, 3584 Utrecht, The Netherlands.
Christoph KönigsDepartment of Paediatrics and Adolescent Medicine, Haemophilia Treatment Centre, Goethe University, 60323 Frankfurt, Germany.
David StephensenKent Haemophilia Centre, East Kent Hospitals University NHS Trust, Canterbury CT1 3NG, UK.ORCID 0000-0002-6175-3343
Paul McLaughlinKatharine Dormandy Haemophilia Centre and Thrombosis Unit, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
Gaetan DuportAssociation Française des Hemophiles, 75739 Paris, France.ORCID 0000-0001-9632-8331
Cédric HermansHemostasis and Thrombosis Unit, Division of Hematology, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium.
Maria Elisa MancusoCenter for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.
Cliniques Universitaires Saint-Luc · BEAssociation Française de Chirurgie · FRBarts Health NHS Trust · GBGoethe University Frankfurt · DEIRCCS Humanitas Research Hospital · ITRoyal Free London NHS Foundation Trust · GBUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The physiotherapist plays an essential role for people with haemophilia, an inherited bleeding disease responsible for musculoskeletal complications. Yet, with the advent of new and advanced therapies, the medical landscape is changing, and physiotherapy must adapt alongside. This paper considers whether there will still be a need for physiotherapy in the era of advanced therapies, and discusses ways in which services should evolve to complement emerging treatment paradigms for haemostasis in people with haemophilia. Ultimately, physiotherapy will remain an important element of care, even for people with little joint damage and low risks in the era of the new mild phenotype. However, competencies will need to evolve, and physiotherapists in both primary care and specialist treatment centres should work with haematology colleagues to develop more sensitive tools for detecting early joint changes. Physiotherapists will also play a crucial role in counselling and physically coaching, monitoring the musculoskeletal status of people with haemophilia who have transitioned to new treatments.

Indexed as

EHL concentratesemicizumabgene therapyhaemophiliaphysiotherapytrough levels

Identifiers

PMID34206923
PMCPMC8267623
OpenAlexW3175880017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.