SynthesisInternational journal of environmental research and public health2021
Systematic Review on Healthcare and Societal Costs of Tinnitus.
Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effectiveness of Telerehabilitation Interventions for Self-Management of Tinnitus: Update of a Systematic Review.Journal of medical Internet research · 2026Pooled it
- Effectiveness of Telerehabilitation Interventions for Self-management of Tinnitus: Systematic Review.Journal of medical Internet research · 2023Pooled it
- A clinical trial of a patient-customized virtual reality intervention for tinnitus.Scientific reports · 2022Trial
- Tinnitus in urban settings: insights into lifestyle and medical factors from the Hamburg City Health Study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Four decades of tinnitus pathology research: a bibliometric analysis of scientific trends, collaborations, and research hotspots.International journal of emergency medicine · 2026Review
- Tinnitus and tinnitus disorder: Genetic, neurobiological, and clinical differentiation.iScience · 2026Review
- Association between serum α-Klotho levels and tinnitus stratified by sex and depression: A cross-sectional study from NHANES.Medicine · 2026Article
- Exploring the Impact of Tinnitus on Work Productivity.Brain sciences · 2026Article
- Somatosensory Intervention Targeting Temporomandibular Disorders and Awake Bruxism Positively Impacts Subjective Tinnitus.Audiology research · 2025Article
- Korean medicine combination treatment for chronic tinnitus unresponsive to conventional treatment: A case report and review of literature.World journal of clinical cases · 2025Article
- Digital Therapeutics in Tinnitus Care: A Feasibility Study of the Oto Smartphone Application.Journal of the American Academy of Audiology · 2025Article
- Review
- Research trends and hotspots of cognitive behavioral therapy for tinnitus: a bibliometric analysis.Frontiers in neuroscience · 2025Article
- A U-shaped relationship between sleep duration and tinnitus incidence: analysis of 13,871 participants from NHANES.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
- The Out-of-pocket Expenses of People With Tinnitus in Europe.Journal of epidemiology · 2024Article
- Current understanding of subjective tinnitus in adults.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Review
- Establishing a Comprehensive Tinnitus Care Pathway-Part 1: Essential Components.Seminars in hearing · 2024Review
- Tinnitus: Clinical Insights in Its Pathophysiology-A Perspective.Journal of the Association for Research in Otolaryngology : JARO · 2024Review
- Using Participatory Action Research to Redirect Tinnitus Treatment and Research-An Interview Study.Journal of clinical medicine · 2024Article
- Electrical Ear Canal Stimulation as a Therapeutic Approach for Tinnitus-A Proof of Concept Study.Journal of clinical medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tinnitus disability is a heterogeneous and complex condition, affecting more than 10% and compromising the quality of life of 2% of the population, with multiple contributors, often unknown, and enigmatic pathophysiology. The available treatment options are unsatisfactory, as they can, at best, reduce tinnitus severity, but not eliminate its perception. Given the spread of tinnitus and the lack of a standardized treatment, it is crucial to understand the economic burden of this condition. We conducted a systematic review of the literature on PubMed/MEDLINE, Embase, the Cochrane Database of Systematic Reviews (CDSR) and Google Scholar, in order to identify all the articles published on the economic burden of tinnitus before 1 April 2021 (PROSPERO-International prospective register of systematic reviews-No: CRD42020180438). Out of 273 articles identified through our search strategy, only five articles from studies conducted in the United States of America (USA), the Netherlands and the United Kingdom (UK) provided data on tinnitus's economic costs. Three studies provided mean annual estimates per patient ranging between EUR 1544 and EUR 3429 for healthcare costs, between EUR 69 and EUR 115 for patient and family costs and between EUR 2565 and EUR 3702 for indirect costs, including productivity loss. The other two studies reported an annual mean cost of EUR 564 per patient for tinnitus-related clinical visits, and total costs of EUR 1388 and EUR 3725 for patients treated with a sound generator and Neuromonics Tinnitus Treatment, respectively. Our comprehensive review shows a gap in the knowledge about the economic burden of tinnitus on healthcare systems, patients and society. The few available studies show considerable expenses due to healthcare and indirect costs, while out-of-pocket costs appear to be less financially burdensome. Comprehensive health economic evaluations are needed to fill the gaps in current knowledge, using a unified method with reliable and standardized tools.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.