Evidence map›Paper›PMID 34206899›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Eye Infections Caused by Filamentous Fungi: Spectrum and Antifungal Susceptibility of the Prevailing Agents in Germany.

Grit Walther, Anna Zimmermann, Johanna Theuersbacher, Kerstin Kaerger, Marie von Lilienfeld-Toal, Mathias Roth, Daniel Kampik, Gerd Geerling, Oliver Kurzai

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  7. Antimicrobial agents and chemotherapy · 2025
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  11. Fusarium spp.: infections and intoxications.GMS infectious diseases · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. First Report of a Case of Ocular Infection Caused byPathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Grit WaltherNational Reference Center for Invasive Fungal Infections (NRZMyk), Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Adolf-Reichwein-Str. 23, 07745 Jena, Germany.
Anna ZimmermannInstitute for Hygiene and Microbiology, University of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0001-8656-9756
Johanna TheuersbacherDepartment of Ophthalmology, University Hospital Würzburg, 97080 Würzburg, Germany.
Kerstin KaergerNational Reference Center for Invasive Fungal Infections (NRZMyk), Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Adolf-Reichwein-Str. 23, 07745 Jena, Germany.
Marie von Lilienfeld-ToalNational Reference Center for Invasive Fungal Infections (NRZMyk), Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Adolf-Reichwein-Str. 23, 07745 Jena, Germany.
Mathias RothDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0003-1993-1289
Daniel KampikDepartment of Ophthalmology, University Hospital Würzburg, 97080 Würzburg, Germany.
Gerd GeerlingDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0003-2034-3687
Oliver KurzaiNational Reference Center for Invasive Fungal Infections (NRZMyk), Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Adolf-Reichwein-Str. 23, 07745 Jena, Germany.ORCID 0000-0002-7277-2646
Heinrich Heine University Düsseldorf · DELeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEUniversitätsklinikum Würzburg · DEUniversity of Würzburg · DEJena University Hospital · DE

Funding

Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg D-420Robert-Koch-Institute 1369-240
6 · The paper itself

Abstract

Fungal eye infections can lead to loss of vision and blindness. The disease is most prevalent in the tropics, although case numbers in moderate climates are increasing as well. This study aimed to determine the dominating filamentous fungi causing eye infections in Germany and their antifungal susceptibility profiles in order to improve treatment, including cases with unidentified pathogenic fungi. As such, we studied all filamentous fungi isolated from the eye or associated materials that were sent to the NRZMyk between 2014 and 2020. All strains were molecularly identified and antifungal susceptibility testing according to the EUCAST protocol was performed for common species. In total, 242 strains of 66 species were received.

Indexed as

Alternariaantifungal susceptibilityAspergilluseye infectionfungal infectionFusariumkeratitisnatamycinPurpureocilliumScedosporium

Identifiers

PMID34206899
PMCPMC8307352
OpenAlexW3177077406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.