Evidence map›Paper›PMID 34206897›Full record

ArticlePharmaceutics2021

Structure-Activity Relationship and Molecular Docking of a Kunitz-Like Trypsin Inhibitor, Kunitzin-AH, from the Skin Secretion of

Yuqing Chen, Xinping Xi, Chengbang Ma, Mei Zhou, Xiaoling Chen, Zhuming Ye, Lilin Ge, Qinan Wu, Tianbao Chen, Lei Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Yuqing ChenSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Xinping XiSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Chengbang MaSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Mei ZhouSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.ORCID 0000-0003-2576-0252
Xiaoling ChenSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Zhuming YeSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Lilin GeCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Qinan WuCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Tianbao ChenSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.ORCID 0000-0001-8011-9260
Lei WangSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.ORCID 0000-0002-8811-8489
Hang Fai KwokInstitute of Translational Medicine, Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau, China.ORCID 0000-0002-6349-4517
Queen's University Belfast · GBNanjing University of Chinese Medicine · CNUniversity of Macau · MO

Funding

Fundo para o Desenvolvimento das Ciências e da Tecnologia 0055/2019/A1Fundo para o Desenvolvimento das Ciências e da Tecnologia 019/2017/A1
6 · The paper itself

Abstract

Kunitz-like trypsin inhibitors are one of the most noteworthy research objects owing to their significance in pharmacological studies, including anticarcinogenic activity, obesity regulation and anticoagulation. In the current study, a novel Kunitz-like trypsin inhibitor, Kunitzin-AH, was isolated from the skin secretion of

Indexed as

Kunitz-like trypsin inhibitorsmolecular dockingstructure–activity relationship

Identifiers

PMID34206897
PMCPMC8309051
OpenAlexW3174884159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.