Evidence map›Paper›PMID 34206846›Full record

ArticleNutrients2021

Inflammatory Potential of the Diet and Incidence of Crohn's Disease and Ulcerative Colitis in the EPIC-Spain Cohort.

Marcela Guevara, Elena Salamanca-Fernández, Estrella Miqueleiz, Diana Gavrila, Pilar Amiano, Catalina Bonet, Miguel Rodríguez-Barranco, José María Huerta, Luis Bujanda, María José Sánchez and 4 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Life's essential 8, genetic susceptibility, and risk of inflammatory bowel diseases: a population-based cohort study.The international journal of behavioral nutrition and physical activity · 2024
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Marcela GuevaraInstituto de Salud Pública de Navarra, 31003 Pamplona, Spain.ORCID 0000-0001-9242-6364
Elena Salamanca-FernándezInstituto de Investigación Biosanitaria de Granada (ibs.GRANADA), 18012 Granada, Spain.
Estrella MiqueleizInstituto de Salud Pública de Navarra, 31003 Pamplona, Spain.
Diana GavrilaConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.
Pilar AmianoConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.
Catalina BonetUnit of Nutrition and Cancer, Catalan Institute of Oncology-ICO, and Nutrition and Cancer Group, Epidemiology, Public Health, Cancer Prevention and Palliative Care Program, Bellvitge Biomedical Research Institute-IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.
Miguel Rodríguez-BarrancoConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0002-9972-9779
José María HuertaConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0002-9637-3869
Luis BujandaDepartment of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute, 20014 San Sebastian, Spain.
María José SánchezConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0003-4817-0757
María Dolores ChirlaqueConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.
Antonio AgudoUnit of Nutrition and Cancer, Catalan Institute of Oncology-ICO, and Nutrition and Cancer Group, Epidemiology, Public Health, Cancer Prevention and Palliative Care Program, Bellvitge Biomedical Research Institute-IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.
Eva ArdanazInstituto de Salud Pública de Navarra, 31003 Pamplona, Spain.
Jesús CastillaInstituto de Salud Pública de Navarra, 31003 Pamplona, Spain.ORCID 0000-0002-6396-7265
Instituto de Salud Pública de Navarra · ESInstituto Murciano de Investigación Biosanitaria · ESInstitut d'Investigació Biomédica de Bellvitge · ESInstituto de Investigación Biosanitaria de Granada · ESBasque Government · ESUniversidad de Granada · ESUniversity of the Basque Country · ES

Funding

Crohn's and Colitis UK M2017-2Instituto de Salud Carlos III PIE14/00045International Agency for Research on Cancer AEP/93/06Intra-CIBERESP mobility program ESPF60/2017
6 · The paper itself

Abstract

Diet may influence the development of inflammatory bowel disease through the modulation of inflammation. We investigated whether the inflammatory potential of the diet is associated with the risk of Crohn's disease (CD) and ulcerative colitis (UC) in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain). The study included 32,633 participants aged 29-69 years. The inflammatory potential of the diet was measured by using an inflammatory score of the diet (ISD) based on a baseline dietary history questionnaire. Cox regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). During 21 years (674,547 person-years) of follow-up, 32 and 57 participants developed CD and UC, respectively. In multivariable analysis, a one-standard deviation (SD) increment in the ISD (two-unit increase) was associated with a higher risk of CD (HR of 1.71; 95% CI: 1.05-2.80;

Indexed as

DietAdultAgedColitis, UlcerativeCrohn DiseaseFemaleHumansIncidenceInflammationInflammatory Bowel DiseasesMaleMiddle AgedNeoplasmsNutrition AssessmentProportional Hazards ModelsProspective StudiesCrohn’s diseaseinflammationinflammatory bowel diseaseinflammatory potential of the dietprospective cohort studyulcerative colitis

Identifiers

PMID34206846
PMCPMC8308349
OpenAlexW3177272123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.