Evidence map›Paper›PMID 34206780›Full record

ArticleInternational journal of molecular sciences2021

Lanthionine, a Novel Uremic Toxin, in the Vascular Calcification of Chronic Kidney Disease: The Role of Proinflammatory Cytokines.

Alessandra Fortunata Perna, Luigi Russo, Vittoria D'Esposito, Pietro Formisano, Dario Bruzzese, Carmela Vigorito, Annapaola Coppola, Patrizia Lombari, Domenico Russo, Diego Ingrosso

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Observational
  3. Review
  4. Assessment of Eotaxin Concentration in Children with Chronic Kidney Disease.International journal of molecular sciences · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Cysteine as a Multifaceted Player in Kidney, theMolecules (Basel, Switzerland) · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Alessandra Fortunata PernaFirst Division of Nephrology, Department of Medical Translational Sciences, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Luigi RussoDivision of Nephrology, Federico II University, 80131 Naples, Italy.
Vittoria D'EspositoDepartment of Medical Translational Sciences, Federico II University & CNR/IEOS, 80131 Naples, Italy.
Pietro FormisanoDepartment of Medical Translational Sciences, Federico II University & CNR/IEOS, 80131 Naples, Italy.
Dario BruzzeseDepartment of Public Health, Federico II University, 80131 Naples, Italy.ORCID 0000-0001-9911-4646
Carmela VigoritoFirst Division of Nephrology, Department of Medical Translational Sciences, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Annapaola CoppolaDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.
Patrizia LombariFirst Division of Nephrology, Department of Medical Translational Sciences, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Domenico RussoDivision of Nephrology, Federico II University, 80131 Naples, Italy.
Diego IngrossoDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.
Federico II University Hospital · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular calcification (VC) is a risk factor for cardiovascular events and mortality in chronic kidney disease (CKD). Several components influence the occurrence of VC, among which inflammation. A novel uremic toxin, lanthionine, was shown to increase intracellular calcium in endothelial cells and may have a role in VC. A group of CKD patients was selected and divided into patients with a glomerular filtration rate (GFR) of <45 mL/min/1.73 m

Indexed as

AdultAlanineBiomarkersCytokinesFemaleGlomerular Filtration RateHumansMaleRenal Insufficiency, ChronicSulfidesVascular CalcificationAlanineBiomarkersCytokineslanthionineSulfideschronic kidney diseasecytokineshemodialysislanthioninevascular calcification

Identifiers

PMID34206780
PMCPMC8269354
OpenAlexW3175330728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.