ArticleInternational journal of molecular sciences2021
Life and Death of Immature Neurons in the Juvenile and Adult Primate Amygdala.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- Disrupted maternal care alters neural-microglia interactions in the primate paralaminar (PL) nucleus of the amygdala.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Immature Excitatory Neurons in the Postnatal Ferret Paralaminar Nuclei and Their Relationship to the Amygdala Across Species.The Journal of comparative neurology · 2026Article
- Review
- Postnatal Development of the Perirhinal and Parahippocampal Cortices: A Stereological Study in Macaque Monkeys.The Journal of comparative neurology · 2026Article
- Multispecies characterization of immature neurons in the mammalian amygdala reveals their expansion in primates.PLoS biology · 2025Article
- Microglia Morphology in the Developing Primate Amygdala and Effects of Early Life Stress.eNeuro · 2025Article
- Adult neurogenesis and "immature" neurons in mammals: an evolutionary trade-off in plasticity?Brain structure & function · 2024Review
- Stereological Analysis of the Rhesus Monkey Perirhinal and Parahippocampal Cortices.The Journal of comparative neurology · 2024Article
- Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala.Neuron · 2024Article
- Which neurodevelopmental processes continue in humans after birth?Frontiers in neuroscience · 2024Article
- Maternal Perinatal Stress Associated With Offspring Negative Emotionality, But the Underlying Mechanisms Remain Elusive.The American journal of psychiatry · 2023Article
- Structural plasticity in the entorhinal and perirhinal cortices following hippocampal lesions in rhesus monkeys.Hippocampus · 2023Article
- Light Alcohol Consumption Promotes Early Neurogenesis Following Ischemic Stroke in Adult C57BL/6J Mice.Biomedicines · 2023Article
- Immature neurons in the primate amygdala: changes with early development and disrupted early environment.bioRxiv : the preprint server for biology · 2023Article
- Immature excitatory neurons in the amygdala come of age during puberty.Developmental cognitive neuroscience · 2022Article
- Neuronal and Brain Maturation.International journal of molecular sciences · 2022Article
- UBIAD1 alleviates ferroptotic neuronal death by enhancing antioxidative capacity by cooperatively restoring impaired mitochondria and Golgi apparatus upon cerebral ischemic/reperfusion insult.Cell & bioscience · 2022Article
- How Widespread Are the "Young" Neurons of the Mammalian Brain?Frontiers in neuroscience · 2022Article
- Review
- Brain Plasticity in Humans and Model Systems: Advances, Challenges, and Future Directions.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
In recent years, a large population of immature neurons has been documented in the paralaminar nucleus of the primate amygdala. A substantial fraction of these immature neurons differentiate into mature neurons during postnatal development or following selective lesion of the hippocampus. Notwithstanding a growing number of studies on the origin and fate of these immature neurons, fundamental questions about the life and death of these neurons remain. Here, we briefly summarize what is currently known about the immature neurons present in the primate ventral amygdala during development and in adulthood, as well as following selective hippocampal lesions. We provide evidence confirming that the distribution of immature neurons extends to the anterior portions of the entorhinal cortex and layer II of the perirhinal cortex. We also provide novel arguments derived from stereological estimates of the number of mature and immature neurons, which support the view that the migration of immature neurons from the lateral ventricle accompanies neuronal maturation in the primate amygdala at all ages. Finally, we propose and discuss the hypothesis that increased migration and maturation of neurons in the amygdala following hippocampal dysfunction may be linked to behavioral alterations associated with certain neurodevelopmental disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.