Evidence map›Paper›PMID 34206530›Full record

ArticleCells2021

Exogenous Vitamins K Exert Anti-Inflammatory Effects Dissociated from Their Role as Substrates for Synthesis of Endogenous MK-4 in Murine Macrophages Cell Line.

Anna Kieronska-Rudek, Agnieszka Kij, Patrycja Kaczara, Anna Tworzydlo, Marek Napiorkowski, Katarzyna Sidoryk, Stefan Chlopicki

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anna Kieronska-RudekJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.
Agnieszka KijJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.ORCID 0000-0003-2233-0564
Patrycja KaczaraJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.ORCID 0000-0003-0106-4172
Anna TworzydloJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.ORCID 0000-0002-0638-9008
Marek NapiorkowskiChemistry Department, Pharmaceutical Research Institute, Rydygiera 8, 01-793 Warszawa, Poland.
Katarzyna SidorykChemistry Department, Pharmaceutical Research Institute, Rydygiera 8, 01-793 Warszawa, Poland.ORCID 0000-0002-1581-0693
Stefan ChlopickiJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.ORCID 0000-0002-2878-3858
Jagiellonian University · PLInstytut Farmaceutyczny · PL

Funding

BioS Priority Research Area at the Jagiellonian University in Krakow "Excellence Initiative - Research University"Narodowe Centrum Badań i Rozwoju POWR.03.02.00-00-I013/16Narodowe Centrum Nauki 2018/29/B/NZ7/01684Narodowe Centrum Nauki 2018/31/N/NZ7/03900
6 · The paper itself

Abstract

Vitamins K exert a range of activities that extend far beyond coagulation and include anti-inflammatory effects, but the mechanisms involved in anti-inflammatory action remain unclear. In the present study, we showed that various forms of exogenous vitamins-K

Indexed as

AnimalsAnti-Inflammatory AgentsAtorvastatinCell RespirationCyclooxygenase 2CytokinesEicosanoidsEnzyme InductionLipopolysaccharidesMacrophagesMatrix Metalloproteinase 2Matrix Metalloproteinase 9MiceMitochondriaNitric OxideNitric Oxide Synthase Type IIAnti-Inflammatory AgentsAtorvastatinCyclooxygenase 2CytokinesEicosanoidsLipopolysaccharidesMatrix Metalloproteinase 2Matrix Metalloproteinase 9Nitric OxideNitric Oxide Synthase Type IIVitamin Kendogenous MK-4inflammationmacrophagesstatinvitamins K

Identifiers

PMID34206530
PMCPMC8303864
OpenAlexW3176772319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.