Evidence map›Paper›PMID 34206474›Full record

ReviewAntibiotics (Basel, Switzerland)2021

CRISPR-Cas, a Revolution in the Treatment and Study of ESKAPE Infections: Pre-Clinical Studies.

Manuel González de Aledo, Mónica González-Bardanca, Lucía Blasco, Olga Pacios, Inés Bleriot, Laura Fernández-García, Melisa Fernández-Quejo, María López, Germán Bou, María Tomás

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Advances in CRISPR-Cas for Diagnosis and Treatment ofPathogens (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Phages and quorum sensing: findings to consider in phage therapy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. CRISPR-Based Gene Editing inPharmaceuticals (Basel, Switzerland) · 2023
    Review
  9. Review
  10. Review
  11. Application of CRISPR-Cas system in the diagnosis and therapy of ESKAPE infections.Frontiers in cellular and infection microbiology · 2023
    Review
  12. Review
  13. Review
  14. Review
  15. The Spread of Antibiotic Resistance Genes In Vivo Model.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Manuel González de AledoMicrobiology Department-A Coruña University Hospital (CHUAC), 15006 A Coruña, Spain.ORCID 0000-0001-7222-4941
Mónica González-BardancaMicrobiology Department-A Coruña University Hospital (CHUAC), 15006 A Coruña, Spain.
Lucía BlascoA Coruña Biomedical Research Institute (INIBIC), University of A Coruña (UDC), 15006 A Coruña, Spain.ORCID 0000-0002-4039-4142
Olga PaciosA Coruña Biomedical Research Institute (INIBIC), University of A Coruña (UDC), 15006 A Coruña, Spain.ORCID 0000-0002-4476-856X
Inés BleriotA Coruña Biomedical Research Institute (INIBIC), University of A Coruña (UDC), 15006 A Coruña, Spain.ORCID 0000-0002-1846-4693
Laura Fernández-GarcíaA Coruña Biomedical Research Institute (INIBIC), University of A Coruña (UDC), 15006 A Coruña, Spain.ORCID 0000-0002-8531-6105
Melisa Fernández-QuejoMicrobiology Department-A Coruña University Hospital (CHUAC), 15006 A Coruña, Spain.
María LópezA Coruña Biomedical Research Institute (INIBIC), University of A Coruña (UDC), 15006 A Coruña, Spain.
Germán BouMicrobiology Department-A Coruña University Hospital (CHUAC), 15006 A Coruña, Spain.
María TomásMicrobiology Department-A Coruña University Hospital (CHUAC), 15006 A Coruña, Spain.ORCID 0000-0003-4501-0387

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the biggest threats we face globally is the emergence of antimicrobial-resistant (AMR) bacteria, which runs in parallel with the lack in the development of new antimicrobials. Among these AMR bacteria pathogens belonging to the ESKAPE group can be highlighted (

Indexed as

CRISPR-CasESKAPE pathogenstreatment

Identifiers

PMID34206474
PMCPMC8300728

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.