ReviewMolecules (Basel, Switzerland)2021
Alkaloids in Contemporary Drug Discovery to Meet Global Disease Needs.
Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Alkaloids as Emerging Neuroprotective Agents for Neurodegenerative Disorders: Insights into Tryptanthrin and Its Derivatives.International journal of molecular sciences · 2026Review
- Divergent and precise alkaloid remodelling with a small suite of reactions.Nature chemistry · 2026Article
- Organosulfur compounds as dual-action agents: a critical review of antimicrobial and immunomodulatory potentials, and translational barriers.Frontiers in pharmacology · 2026Review
- Profiling the Complexity of Resistance Factors in Cancer Cells Towards Berberine and Its Derivatives.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Beyond phylogeny: phytochemical diversity as a unique metric for biodiversity in the Gentianales.The New phytologist · 2025Article
- Discovery of Potential Antileishmanial Compounds Through Phenotypic Screening of an Alkaloid Library.Molecules (Basel, Switzerland) · 2025Article
- Tetracyclic Bis-Piperidine Alkaloids: Structures, Bioinspired Synthesis, Synthesis, and Bioactivities.Molecules (Basel, Switzerland) · 2025Review
- Drug-drug interactions of plant alkaloids derived from herbal medicines on the phase II UGT enzymes: an introductory review.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Review
- "We Cure Sickle Cell Disease with Herbs": Perspectives of Herbal Medicine Practitioners Treating Sickle Cell Disease in the Acholi Sub-Region.Journal of multidisciplinary healthcare · 2025Article
- In Vitro Antiprotozoal Activity ofPlants (Basel, Switzerland) · 2024Article
- The contemporary nexus of medicines security and bioprospecting: a future perspective for prioritizing the patient.Natural products and bioprospecting · 2024Review
- Molecular Hybridization of Alkaloids Using 1,2,3-Triazole-Based Click Chemistry.Molecules (Basel, Switzerland) · 2023Review
- Sustainable biosynthetic pathways to value-added bioproducts from hydroxycinnamic acids.Applied microbiology and biotechnology · 2023Review
- Application of Metabolite-Responsive Biosensors for Plant Natural Products Biosynthesis.Biosensors · 2023Review
- A roadmap to establish a comprehensive platform for sustainable manufacturing of natural products in yeast.Nature communications · 2023Review
- Papaverinol-Molecules (Basel, Switzerland) · 2023Article
- Machine learning enhances prediction of plants as potential sources of antimalarials.Frontiers in plant science · 2023Article
- Deciphering anti-infectious compounds from Peruvian medicinalFrontiers in pharmacology · 2023Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An overview is presented of the well-established role of alkaloids in drug discovery, the application of more sustainable chemicals, and biological approaches, and the implementation of information systems to address the current challenges faced in meeting global disease needs. The necessity for a new international paradigm for natural product discovery and development for the treatment of multidrug resistant organisms, and rare and neglected tropical diseases in the era of the Fourth Industrial Revolution and the Quintuple Helix is discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.