Evidence map›Paper›PMID 34206459›Full record

ArticleMolecules (Basel, Switzerland)2021

Cost-Effective Production of L-DOPA by Tyrosinase-Immobilized Polyhydroxyalkanoate Nanogranules in Engineered

Jiping Zhao, Ganqiao Ran, Mengmeng Xu, Xiaoyun Lu, Dan Tan

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jiping ZhaoKey Laboratory of Biomedical Information Engineering of the Ministry of Education, Department of Biological Science and Bioengineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Ganqiao RanInstitute of Bio-Agriculture of Shaanxi Province, Xi'an 710043, China.
Mengmeng XuKey Laboratory of Biomedical Information Engineering of the Ministry of Education, Department of Biological Science and Bioengineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Xiaoyun LuKey Laboratory of Biomedical Information Engineering of the Ministry of Education, Department of Biological Science and Bioengineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.ORCID 0000-0003-3284-4729
Dan TanKey Laboratory of Biomedical Information Engineering of the Ministry of Education, Department of Biological Science and Bioengineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.ORCID 0000-0003-4364-7843
Xi'an Jiaotong University · CNMicrobiology Institute of Shaanxi · CN

Funding

Ministry of Science and Technology of China 2018YFA0900200National Natural Science Foundation of China 21306110National Natural Science Foundation of China 21602171National Natural Science Foundation of Shaanxi Province 2020JQ-027Scientific Research Projects of Shaanxi Academy of Science 2017K-13Scientific Research Projects of Shaanxi Academy of Science 2019K-09
6 · The paper itself

Abstract

3,4-dihydroxyphenyl-L-alanine (L-DOPA) is a preferred drug for Parkinson's disease, with an increasing demand worldwide that mainly relies on costly and environmentally problematic chemical synthesis. Yet, biological L-DOPA production is unfeasible at the industrial scale due to its low L-DOPA yield and high production cost. In this study, low-cost

Indexed as

Bacterial ProteinsEnzymes, ImmobilizedHalomonasMicroorganisms, Genetically-ModifiedMonophenol MonooxygenaseNanoparticlesPolyhydroxyalkanoatesLevodopaVerrucomicrobiaBacterial ProteinsEnzymes, ImmobilizedLevodopaMonophenol MonooxygenasePolyhydroxyalkanoatesHalomonas bluephagenesisimmobilizationL-DOPApolyhydroxyalkanoatestyrosinase

Identifiers

PMID34206459
PMCPMC8270294
OpenAlexW3174245956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.