Evidence map›Paper›PMID 34206369›Full record

ArticleInternational journal of molecular sciences2021

Expression Profile of New Marker Genes Involved in Differentiation of Canine Adipose-Derived Stem Cells into Osteoblasts.

Maurycy Jankowski, Mariusz Kaczmarek, Grzegorz Wąsiatycz, Claudia Dompe, Paul Mozdziak, Jędrzej M Jaśkowski, Hanna Piotrowska-Kempisty, Bartosz Kempisty

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Bone Metastasis Challenge: New Ideas and Future.International journal of molecular sciences · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Maurycy JankowskiDepartment of Anatomy, Poznan University of Medical Sciences, 60-781 Poznan, Poland.ORCID 0000-0001-9476-0235
Mariusz KaczmarekDepartment of Cancer Immunology, Chair of Medical Biotechnology, Poznan University of Medical Sciences, 61-866 Poznan, Poland.ORCID 0000-0002-6282-3251
Grzegorz WąsiatyczDepartment of Veterinary Surgery, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.
Claudia DompeThe School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Paul MozdziakPrestage Department of Poultry Science, College of Agriculture and Life Sciences, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0000-0002-1575-3123
Jędrzej M JaśkowskiDepartment of Diagnostics and Clinical Sciences, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Hanna Piotrowska-KempistyDepartment of Toxicology, Poznan University of Medical Sciences, 60-701 Poznan, Poland.
Bartosz KempistyDepartment of Anatomy, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Poznan University of Medical Sciences · PLNicolaus Copernicus University · PLNorth Carolina State University · USUniversity of Aberdeen · GB

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego DI2017018647
6 · The paper itself

Abstract

Next-generation sequencing (RNAseq) analysis of gene expression changes during the long-term in vitro culture and osteogenic differentiation of ASCs remains to be important, as the analysis provides important clues toward employing stem cells as a therapeutic intervention. In this study, the cells were isolated from adipose tissue obtained during routine surgical procedures and subjected to 14-day in vitro culture and differentiation. The mRNA transcript levels were evaluated using the Illumina platform, resulting in the detection of 19,856 gene transcripts. The most differentially expressed genes (fold change >|2|, adjusted

Indexed as

TranscriptomeAdipose TissueAnimalsCell DifferentiationDogsGene Expression ProfilingGene Expression RegulationOsteoblastsOsteogenesisSequence Analysis, RNAStem CellsadiposeanalysisRNAseqstem cellstranscriptome

Identifiers

PMID34206369
PMCPMC8269079
OpenAlexW3173777877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.