Evidence map›Paper›PMID 34206327›Full record

ArticleMolecules (Basel, Switzerland)2021

4,7-Disubstituted 7

Ruben Soto-Acosta, Eunkyung Jung, Li Qiu, Daniel J Wilson, Robert J Geraghty, Liqiang Chen

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Discovery of pyrrolo[2,3-d]pyrimidine derivatives with inhibitory effect on liver cancer stem cell.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
  2. Network Pharmacology-Guided Identification ofInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Zika Virus Inhibitors Based on a 1,3-Disubstituted 1Molecules (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Searching Anti-Zika Virus Activity in 1Molecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ruben Soto-AcostaCenter for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Eunkyung JungCenter for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Li QiuCenter for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Daniel J WilsonCenter for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Robert J GeraghtyCenter for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-0560-6509
Liqiang ChenCenter for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-4229-863X
University of Minnesota · US

Funding

Optimizing Zika NS5 Methyltransferase InhibitorsR21AI151427 · NIAID · UNIVERSITY OF MINNESOTA · PI CHEN, LIQIANG · 2020 to 2021
$424k
NIAID NIH HHS R21 AI151427
6 · The paper itself

Abstract

Discovery of compound

Indexed as

Antiviral AgentsPyrimidinesCell Line, TumorHumansVirus ReplicationZika VirusZika Virus InfectionAntiviral AgentsPyrimidinesantiviral agentsdengue virusflavivirusZika virus

Identifiers

PMID34206327
PMCPMC8270260
OpenAlexW3176057019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.