Evidence map›Paper›PMID 34206285›Full record

ReviewPharmaceutics2021

3D Printing-A "Touch-Button" Approach to Manufacture Microneedles for Transdermal Drug Delivery.

Merima Sirbubalo, Amina Tucak, Kenan Muhamedagic, Lamija Hindija, Ognjenka Rahić, Jasmina Hadžiabdić, Ahmet Cekic, Derzija Begic-Hajdarevic, Maida Cohodar Husic, Almir Dervišević and 1 more

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  11. Recent progress of polymeric microneedle-assisted long-acting transdermal drug delivery.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Merima SirbubaloDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0001-8558-2633
Amina TucakDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0002-5149-8860
Kenan MuhamedagicDepartment of Mechanical Production Engineering, Faculty of Mechanical Engineering, University of Sarajevo, Vilsonovo Setaliste 9, 71000 Sarajevo, Bosnia and Herzegovina.
Lamija HindijaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0002-8755-4692
Ognjenka RahićDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0003-0183-1124
Jasmina HadžiabdićDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0002-9565-153X
Ahmet CekicDepartment of Mechanical Production Engineering, Faculty of Mechanical Engineering, University of Sarajevo, Vilsonovo Setaliste 9, 71000 Sarajevo, Bosnia and Herzegovina.
Derzija Begic-HajdarevicDepartment of Mechanical Production Engineering, Faculty of Mechanical Engineering, University of Sarajevo, Vilsonovo Setaliste 9, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0001-6024-067X
Maida Cohodar HusicDepartment of Mechanical Production Engineering, Faculty of Mechanical Engineering, University of Sarajevo, Vilsonovo Setaliste 9, 71000 Sarajevo, Bosnia and Herzegovina.
Almir DerviševićHead and Neck Surgery, Clinical Center University of Sarajevo, Bolnička 25, 71000 Sarajevo, Bosnia and Herzegovina.
Edina VranićDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0002-5067-8181

Funding

Ministry of Science, Higher Education and Youth of Sarajevo Canton 27-02-11-4375-8/21
6 · The paper itself

Abstract

Microneedles (MNs) represent the concept of attractive, minimally invasive puncture devices of micron-sized dimensions that penetrate the skin painlessly and thus facilitate the transdermal administration of a wide range of active substances. MNs have been manufactured by a variety of production technologies, from a range of materials, but most of these manufacturing methods are time-consuming and expensive for screening new designs and making any modifications. Additive manufacturing (AM) has become one of the most revolutionary tools in the pharmaceutical field, with its unique ability to manufacture personalized dosage forms and patient-specific medical devices such as MNs. This review aims to summarize various 3D printing technologies that can produce MNs from digital models in a single step, including a survey on their benefits and drawbacks. In addition, this paper highlights current research in the field of 3D printed MN-assisted transdermal drug delivery systems and analyzes parameters affecting the mechanical properties of 3D printed MNs. The current regulatory framework associated with 3D printed MNs as well as different methods for the analysis and evaluation of 3D printed MN properties are outlined.

Indexed as

3D printingmicroneedlesprinting materialsprinting parameterstransdermal drug delivery

Identifiers

PMID34206285
PMCPMC8308681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.