Evidence map›Paper›PMID 34206243›Full record

ArticleAnimals : an open access journal from MDPI2021

Alternatives in Education-Rat and Mouse Simulators Evaluated from Course Trainers' and Supervisors' Perspective.

Melanie Humpenöder, Giuliano M Corte, Marcel Pfützner, Mechthild Wiegard, Roswitha Merle, Katharina Hohlbaum, Nancy A Erickson, Johanna Plendl, Christa Thöne-Reineke

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Long-Term Experiences of Basic Education in Laboratory Animal Science.Animals : an open access journal from MDPI · 2025
    Article
  3. Article
  4. A 3D-Printed Dummy for Training Distal Phalanx Amputation in Mice.Animals : an open access journal from MDPI · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Establishment of anFrontiers in bioengineering and biotechnology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Melanie HumpenöderInstitute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.
Giuliano M CorteInstitute of Veterinary Anatomy, Department of Veterinary Medicine, Freie Universität Berlin, 14195 Berlin, Germany.
Marcel PfütznerInstitute of Veterinary Anatomy, Department of Veterinary Medicine, Freie Universität Berlin, 14195 Berlin, Germany.
Mechthild WiegardInstitute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0002-1934-9187
Roswitha MerleInstitute for Veterinary Epidemiology and Biostatistics, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0002-8688-2926
Katharina HohlbaumInstitute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0001-6681-9367
Nancy A EricksonInstitute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.
Johanna PlendlInstitute of Veterinary Anatomy, Department of Veterinary Medicine, Freie Universität Berlin, 14195 Berlin, Germany.
Christa Thöne-ReinekeInstitute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0003-0782-2755

Funding

German Centre for the Protection of Laboratory Animals (Bf3R) 1328-565
6 · The paper itself

Abstract

Simulators allow the inexperienced to practice their skills prior to exercise on live animals. Therefore, they bear great potential in overcoming the dilemma between the present demand for high-quality practical training involving live animals whilst implementing the 3R principle according to the Directive 2010/63/EU. Currently, one mouse and six rat simulators are commercially available. As data on their impact are lacking, this project aimed at providing an overview of the awareness, implementation, and methodical and practical satisfaction provided by 35 course trainers and supervisors of laboratory animal training courses for mice and rats regarding the simulators available. Although simulators facilitate training of relevant techniques and relatively high awareness of them seemed to be present, their implementation is currently very low, possibly due to lack of meeting the respondents' demands. Thus, this study revealed the overall approval of simulator training and general demand for user-optimized, realistic, and financially affordable simulators and, hence, indicates a strong impulse for new developments strengthening the 3Rs as a benefit to all animals used in research.

Indexed as

3R principlealternativeEU Directivehumane educationlaboratory animalsSimulRATorsurveytraining

Identifiers

PMID34206243
PMCPMC8300107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.