Evidence map›Paper›PMID 34206219›Full record

ArticleNutrients2021

Vitamin D Metabolites and Clinical Outcome in Hospitalized COVID-19 Patients.

Sieglinde Zelzer, Florian Prüller, Pero Curcic, Zdenka Sloup, Magdalena Holter, Markus Herrmann, Harald Mangge

Abstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Vitamin D and COVID-19: where are we now?Postgraduate medicine · 2023
    Review
  5. Review
  6. Review
  7. Vitamin D as a Possible COVID-19 Prevention Strategy.International journal of molecular sciences · 2022
    Article
  8. Impaired Vitamin D Metabolism in Hospitalized COVID-19 Patients.Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sieglinde ZelzerClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.ORCID 0000-0002-8653-0779
Florian PrüllerClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.ORCID 0000-0002-3388-0089
Pero CurcicClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.
Zdenka SloupClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.
Magdalena HolterInstitute for Medical Informatics, Statistics and Documentation, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-8355-3617
Markus HerrmannClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.ORCID 0000-0002-3559-9899
Harald ManggeClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.ORCID 0000-0003-4067-247X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Vitamin D, a well-established regulator of calcium and phosphate metabolism, also has immune-modulatory functions. An uncontrolled immune response and cytokine storm are tightly linked to fatal courses of COVID-19. The present retrospective study aimed to inves-tigate vitamin D status markers and vitamin D degradation products in a mixed cohort of 148 hospitalized COVID-19 patients with various clinical courses of COVID-19. (2) Methods: The serum concentrations of 25(OH)D

Indexed as

HospitalizationAgedAged, 80 and overBiomarkersChromatography, LiquidCOVID-19ErgocalciferolsFemaleHumansMaleMiddle AgedRespiration, ArtificialRetrospective StudiesSARS-CoV-2Tandem Mass SpectrometryVitamin DBiomarkersErgocalciferolsVitamin DVitaminsclinical outcomeCOVID19vitamin D metabolites

Identifiers

PMID34206219
PMCPMC8308267

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.