Evidence map›Paper›PMID 34206159›Full record

ArticleAntioxidants (Basel, Switzerland)2021

High-Intensity Interval Training and Moderate-Intensity Continuous Training Attenuate Oxidative Damage and Promote Myokine Response in the Skeletal Muscle of ApoE KO Mice on High-Fat Diet.

Linjia Wang, Jessica Lavier, Weicheng Hua, Yangwenjie Wang, Lijing Gong, Hao Wei, Jianxiong Wang, Maxime Pellegrin, Grégoire P Millet, Ying Zhang

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Exercise-myokine relationships in osteoarthritis.Journal of translational medicine · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Linjia WangSchool of Sport Science, Beijing Sport University, Beijing 100084, China.
Jessica LavierInstitute of Sport Sciences, University of Lausanne, 1015 Lausanne, Switzerland.
Weicheng HuaSchool of Sport Science, Beijing Sport University, Beijing 100084, China.
Yangwenjie WangSchool of Sport Science, Beijing Sport University, Beijing 100084, China.
Lijing GongChina Institute of Sport and Health Science, Beijing Sport University, Beijing 100084, China.
Hao WeiSchool of Sport Science, Beijing Sport University, Beijing 100084, China.
Jianxiong WangFaculty of Health, Engineering, and Sciences, University of Southern Queensland, Toowoomba, QLD 4350, Australia.
Maxime PellegrinDivision of Angiology, Heart and Vessel Department, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland.ORCID 0000-0003-4948-976X
Grégoire P MilletInstitute of Sport Sciences, University of Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0001-8081-4423
Ying ZhangSchool of Sport Science, Beijing Sport University, Beijing 100084, China.
Beijing Sport University · CNUniversity of Lausanne · CHUniversity of Southern Queensland · AU

Funding

Beijing Sport University 2020ZJ007Bilateral Science and Technology Cooperation Programme with Asia and Sino Swiss Science and Technology Cooperation 2020
6 · The paper itself

Abstract

The purpose of this study was to investigate the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on the skeletal muscle in Apolipoprotein E knockout (ApoE KO) and wild-type (WT) C57BL/6J mice. ApoE KO mice fed with a high-fat diet were randomly allocated into: Control group without exercise (ApoE

Indexed as

ApoE KO miceatherosclerosisHIITmyokine productionoxidative damageskeletal muscle

Identifiers

PMID34206159
PMCPMC8300650
OpenAlexW3173949547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.