Evidence map›Paper›PMID 34206141›Full record

ArticleInternational journal of molecular sciences2021

Cross-Linking Effects Dictate the Preference of Galectins to Bind LacNAc-Decorated HPMA Copolymers.

Sara Bertuzzi, Ana Gimeno, Ane Martinez-Castillo, Marta G Lete, Sandra Delgado, Cristina Airoldi, Marina Rodrigues Tavares, Markéta Bláhová, Petr Chytil, Vladimír Křen and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Sara BertuzziCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162 Derio, Bizkaia, Spain.ORCID 0000-0002-4242-7067
Ana GimenoCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162 Derio, Bizkaia, Spain.ORCID 0000-0001-9668-2605
Ane Martinez-CastilloCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162 Derio, Bizkaia, Spain.
Marta G LeteCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162 Derio, Bizkaia, Spain.
Sandra DelgadoCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162 Derio, Bizkaia, Spain.
Cristina AiroldiBioOrgNMR Lab, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.ORCID 0000-0002-3670-6262
Marina Rodrigues TavaresInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovského Nám. 2, 16206 Prague, Czech Republic.ORCID 0000-0002-8099-4820
Markéta BláhováInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovského Nám. 2, 16206 Prague, Czech Republic.ORCID 0000-0002-6141-4309
Petr ChytilInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovského Nám. 2, 16206 Prague, Czech Republic.ORCID 0000-0002-7135-9796
Vladimír KřenInstitute of Microbiology of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.ORCID 0000-0002-1091-4020
Nicola G A AbresciaCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162 Derio, Bizkaia, Spain.
Ana ArdáCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162 Derio, Bizkaia, Spain.ORCID 0000-0003-3027-7417
Pavla BojarováInstitute of Microbiology of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.ORCID 0000-0001-7069-0973
Jesús Jiménez-BarberoCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162 Derio, Bizkaia, Spain.ORCID 0000-0001-5421-8513
CIC bioGUNE · ESCzech Academy of Sciences, Institute of Macromolecular Chemistry · CZIkerbasque · ESCzech Academy of Sciences · CZUniversity of Milano-Bicocca · IT

Funding

Agencia Estatal de Investigación RTI2018-094751-B-C21Agencia Estatal de Investigación RTI2018-095700-B-I00Agencia Estatal de Investigación SEV-2016-0644Akademie Věd České Republiky RP10-Molecules and Materials for LifeEuropean Cooperation in Science and Technology CA17140 and CA16225H2020 European Research Council 788143Hezkuntza, Hizkuntza Politika Eta Kultura Saila, Eusko Jaurlaritza PRE_2018_1_0102Ministerstvo Školství, Mládeže a Tělovýchovy LTC19038 and LTC18041
6 · The paper itself

Abstract

The interaction of multi-LacNAc (Galβ1-4GlcNAc)-containing

Indexed as

AcrylamidesBinding SitesBlood ProteinsCarbohydratesCryoelectron MicroscopyGalectin 1GalectinsHumansLigandsMethacrylatesPolymersProtein BindingAcrylamidesBlood ProteinsCarbohydratesGalectin 1Galectinshydroxypropyl methacrylateLGALS1 protein, humanLGALS3 protein, humanLigandsmethacrylamideMethacrylatesPolymersgalectinglycomimeticglycopolymerHPMA copolymerinhibitionmolecular recognitionmultivalency

Identifiers

PMID34206141
PMCPMC8199549
OpenAlexW3168509851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.