Evidence map›Paper›PMID 34206140›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Nanoceria Prevents Glucose-Induced Protein Glycation in Eye Lens Cells.

Belal I Hanafy, Gareth W V Cave, Yvonne Barnett, Barbara K Pierscionek

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Belal I HanafySchool of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.ORCID 0000-0001-5356-8458
Gareth W V CaveSchool of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.ORCID 0000-0002-4167-1332
Yvonne BarnettFaculty of Heath, Education, Medicine and Social Care and Pharmaceutical Research Group, Medical Technology Research Centre, Anglia Ruskin University, Cambridgeshire CB1 1PT, UK.ORCID 0000-0003-0271-2266
Barbara K PierscionekFaculty of Heath, Education, Medicine and Social Care and Pharmaceutical Research Group, Medical Technology Research Centre, Anglia Ruskin University, Cambridgeshire CB1 1PT, UK.
Nottingham Trent University · GBAnglia Ruskin University · GBUniversity of Staffordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerium oxide nanoparticles (nanoceria) are generally known for their recyclable antioxidative properties making them an appealing biomaterial for protecting against physiological and pathological age-related changes that are caused by reactive oxygen species (ROS). Cataract is one such pathology that has been associated with oxidation and glycation of the lens proteins (crystallins) leading to aggregation and opacification. A novel coated nanoceria formulation has been previously shown to enter the human lens epithelial cells (HLECs) and protect them from oxidative stress induced by hydrogen peroxide (H

Indexed as

cataractcerium oxide nanoparticlesendocytosisglutathioneglycation

Identifiers

PMID34206140
PMCPMC8228845
OpenAlexW3171858211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.