Evidence map›Paper›PMID 34206015›Full record

ArticleMolecules (Basel, Switzerland)2021

Immobilization and Release Studies of Triazole Derivatives from Grafted Copolymer Based on Gellan-Carrying Betaine Units.

Nicolae Baranov, Stefania Racovita, Silvia Vasiliu, Ana Maria Macsim, Catalina Lionte, Valeriu Sunel, Marcel Popa, Jacques Desbrieres, Corina Cheptea

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Polybetaines in Biomedical Applications.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nicolae BaranovDepartment of Natural and Synthetic Polymers, Faculty of Chemical Engineering and Environmental Protection, Gheorghe Asachi Technical University of Iasi, Prof. Dr. Docent Dimitrie Mangeron Street, No. 73, 700050 Iasi, Romania.
Stefania RacovitaDepartment of "Mihai Dima" Functional Polymers, Petru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley, No. 41A, 700487 Iasi, Romania.
Silvia VasiliuDepartment of "Mihai Dima" Functional Polymers, Petru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley, No. 41A, 700487 Iasi, Romania.
Ana Maria MacsimDepartment of "Mihai Dima" Functional Polymers, Petru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley, No. 41A, 700487 Iasi, Romania.ORCID 0000-0002-5107-6369
Catalina LionteFaculty of Medicine, Gr. T. Popa University of Medicine and Pharmacy, Universitatii Street, No.16, 700115 Iasi, Romania.
Valeriu SunelFaculty of Chemistry, Al. I. Cuza University, Carol I Bvd., No. 11, 700506 Iasi, Romania.
Marcel PopaDepartment of Natural and Synthetic Polymers, Faculty of Chemical Engineering and Environmental Protection, Gheorghe Asachi Technical University of Iasi, Prof. Dr. Docent Dimitrie Mangeron Street, No. 73, 700050 Iasi, Romania.ORCID 0000-0003-4929-0830
Jacques DesbrieresInstitut des Sciences Analytiques et de Physico-Chimie pour l'Environnement et les Materiaux (IPREM), Pau and Pays de l'Adour University (UPPA), UMR CNRS 5254, Helioparc Pau Pyrenees, 2 av. President Angot, CEDEX 09, 64053 Pau, France.ORCID 0000-0001-9905-2756
Corina ChepteaDepartment of Biomedical Sciences, Faculty of Biomedical Bioengineering, Gr. T. Popa University of Medicine and Pharmacy, Kogalniceanu Street No. 9-13, 700454 Iasi, Romania.ORCID 0000-0001-8235-6235

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New polymer-bioactive compound systems were obtained by immobilization of triazole derivatives onto grafted copolymers and grafted copolymers carrying betaine units based on gellan and N-vinylimidazole. For preparation of bioactive compound, two new types of heterocyclic thio-derivatives with different substituents were combined in a single molecule to increase the selectivity of the biological action. The 5-aryl-amino-1,3,4 thiadiazole and 5-mercapto-1,2,4-triazole derivatives, each containing 2-mercapto-benzoxazole nucleus, were prepared by an intramolecular cyclization of thiosemicarbazides-1,4 disubstituted in acidic and basic medium. The structures of the new bioactive compounds were confirmed by elemental and spectral analysis (FT-IR and

Indexed as

Anti-Bacterial AgentsBacillus cereusBacillus subtilisBetaineCyclizationEscherichia coliMicrobial Sensitivity TestsPolysaccharides, BacterialSalmonella enteritidisStaphylococcus aureusTriazolesAnti-Bacterial AgentsBetainegellan gumPolysaccharides, BacterialTriazolesadsorption studiesgrafted copolymertriazole derivative

Identifiers

PMID34206015
PMCPMC8199293

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.