Evidence map›Paper›PMID 34205981›Full record

ArticleInternational journal of molecular sciences2021

Longitudinal Changes in Diet Cause Repeatable and Largely Reversible Shifts in Gut Microbial Communities of Laboratory Mice and Are Observed across Segments of the Entire Intestinal Tract.

Adrian Low, Melissa Soh, Sou Miyake, Vanessa Zhi Jie Aw, Jian Feng, Adeline Wong, Henning Seedorf

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Complete genome sequence ofMicrobiology resource announcements · 2023
    Article
  10. Diets, Gut Microbiota and Metabolites.Phenomics (Cham, Switzerland) · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adrian LowTemasek Life Sciences Laboratory, 1 Research Link, Singapore 117604, Singapore.ORCID 0000-0003-0997-2490
Melissa SohTemasek Life Sciences Laboratory, 1 Research Link, Singapore 117604, Singapore.ORCID 0000-0002-7578-9515
Sou MiyakeTemasek Life Sciences Laboratory, 1 Research Link, Singapore 117604, Singapore.
Vanessa Zhi Jie AwTemasek Life Sciences Laboratory, 1 Research Link, Singapore 117604, Singapore.
Jian FengTemasek Life Sciences Laboratory, 1 Research Link, Singapore 117604, Singapore.
Adeline WongTemasek Life Sciences Laboratory, 1 Research Link, Singapore 117604, Singapore.
Henning SeedorfTemasek Life Sciences Laboratory, 1 Research Link, Singapore 117604, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary changes are known to alter the composition of the gut microbiome. However, it is less understood how repeatable and reversible these changes are and how diet switches affect the microbiota in the various segments of the gastrointestinal tract. Here, a treatment group of conventionally raised laboratory mice is subjected to two periods of western diet (WD) interrupted by a period of standard diet (SD) of the same duration. Beta-diversity analyses show that diet-induced microbiota changes are largely reversible (

Indexed as

AnimalsBacillotaBacteroidetesDiet, WesternFecesGastrointestinal MicrobiomeGastrointestinal TractHumansMiceMicrobiotaRNA, Ribosomal, 16SRNA, Ribosomal, 16S16S rRNA gene amplicon sequencingdietary changesgastrointestinal tractMuribaculaceaepredictive metagenomic profilingstandard chowwestern diet

Identifiers

PMID34205981
PMCPMC8198505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.